Investigative Medicine Division
We aim to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Howson LJ. et al, (2018), Nat Commun, 9
Quantification of carotid plaque lipid content with magnetic resonance T2 mapping in patients undergoing carotid endarterectomy.
Alkhalil M. et al, (2017), PLoS One, 12
Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion.
Sutherland BA. et al, (2017), J Cereb Blood Flow Metab, 37, 2494 - 2508
Sezgin E. et al, (2017), Nat Rev Mol Cell Biol, 18, 361 - 374
Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function.
Wang XW. et al, (2017), Clin Exp Dermatol, 42, 622 - 631