Investigative Medicine Division
We aim to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
About AVIC
The Oxford Acute Vascular Imaging Centre (AVIC) at the John Radcliffe Hospital is an internationally unique facility dedicated to clinical research in acute coronary syndromes (heart attack and unstable angina), stroke and transient ischaemic attack (TIA), traumatic brain injury and vascular disorders.
Read moreAbout Us
The Investigative Medicine Division aims to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
Read moreLatest Publications
MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Howson LJ. et al, (2018), Nat Commun, 9
Quantification of carotid plaque lipid content with magnetic resonance T2 mapping in patients undergoing carotid endarterectomy.
Alkhalil M. et al, (2017), PLoS One, 12
Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion.
Sutherland BA. et al, (2017), J Cereb Blood Flow Metab, 37, 2494 - 2508
The mystery of membrane organization: composition, regulation and roles of lipid rafts.
Sezgin E. et al, (2017), Nat Rev Mol Cell Biol, 18, 361 - 374
Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function.
Wang XW. et al, (2017), Clin Exp Dermatol, 42, 622 - 631
Seminars and Events
What's new
Congratulations to our new Professors
7 August 2018
Congratulations to Professor Leanne Hodson (Professor of Metabolic Physiology), Professor Adam Mead (Professor of Haematology) Professor Gary Ford (Professor of Stroke Medicine) and Professor Damian Tyler (Professor of Physiological Metabolism) who were all awarded the title of full professor in the recent Recognition of Distinction.
New research makes progress towards general Salmonella vaccine
21 June 2018
Work by researchers at MRC HIU zeroes in on the mechanisms by which T cells respond to Salmonella infections.
Facebook LIVE: What is a virus?
14 June 2018
Layal and Mirjam in the Rehwinkel lab were live on Facebook to talk about their research on viruses.