Investigative Medicine Division
We aim to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
Head of Division
About AVIC
The Oxford Acute Vascular Imaging Centre (AVIC) at the John Radcliffe Hospital is an internationally unique facility dedicated to clinical research in acute coronary syndromes (heart attack and unstable angina), stroke and transient ischaemic attack (TIA), traumatic brain injury and vascular disorders.
Read moreAbout Us
The Investigative Medicine Division aims to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
Read moreLatest Publications
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MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Howson LJ. et al, (2018), Nat Commun, 9
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Quantification of carotid plaque lipid content with magnetic resonance T2 mapping in patients undergoing carotid endarterectomy.
Alkhalil M. et al, (2017), PLoS One, 12
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Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion.
Sutherland BA. et al, (2017), J Cereb Blood Flow Metab, 37, 2494 - 2508
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The mystery of membrane organization: composition, regulation and roles of lipid rafts.
Sezgin E. et al, (2017), Nat Rev Mol Cell Biol, 18, 361 - 374
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Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function.
Wang XW. et al, (2017), Clin Exp Dermatol, 42, 622 - 631