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Investigative Medicine Division

We aim to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.

Head of Division

COVID-19 research

Structural model of the mosaic-8 RBD-mi3 nanoparticle design. Fan et al., (in press) https://www.biorxiv.org/content/10.1101/2022.06.28.497989v1 Cohen et al., (2022) Science https://www.science.org/doi/10.1126/science.abq0839

Novel all-in-one vaccine developed to tackle future coronavirus threats

Up to $30 million in funding has been announced by the Coalition for Epidemic Preparedness Innovations (CEPI) to bring a new nanoparticle vaccine offering protection against a range of coronaviruses to clinical trial.

A T-cell is shown attacking a SARS-CoV-2 virus.

Strong cytotoxic T cell responses to an internal viral component are associated with mild COVID-19 disease

Study from the Dong Group reveals key differences in the adaptive immune responses of patients with mild vs. severe COVID-19, highlighting a potential new vaccine target.

purple and red cells

Strong immune responses in myeloma patients after two doses of COVID vaccine

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What's new

New research from the Kusumbe Group show lymphatic networks in bone, a tissue previously difficult to study. A number of different bones are shown (L-R) hand, vertebral column, sternum. In all images, blood vessels are shown in red/magenta, and lymphatic vessels are shown in green.

New study reveals role of lymphatic system in bone healing

Bones were thought to lack lymphatic vessels, but new research from the Kusumbe Group published in Cell not only locates them within bone tissue, but demonstrates their role in bone and blood cell regeneration and reveals changes associated with aging.

Anjali Kusumbe receives the RMS Life Sciences Medal

The Royal Microscopical Society awards celebrate the best in microscopy, recognising those making a special contribution to microscopy, cytometry and imaging.

Biotech spinout MiroBio acquired by Gilead Sciences for ~£332m

Co-founded by Simon Davis, MiroBio focuses on developing therapeutics for inflammatory diseases.

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