Investigative Medicine Division
We aim to rapidly translate innovative science into patient benefit across a range of disease areas. From molecular biology and target discovery, through to interventional medicine and informing policy, we bring together researchers in a diverse range of specialties including acute stroke, dementia and immunology.
Head of Division
Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter Anion Exchanger 2 (SLC4A2)
MICHL J. et al, (2023), Cell Reports
Posterior circulation ischaemic stroke diagnosis and management.
Schneider AM. et al, (2023), Clin Med (Lond), 23, 219 - 227
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination.
Yin Z. et al, (2023), Cell Rep, 42
Antibody and memory B cell responses to the dengue virus NS1 antigen in individuals with varying severity of past infection.
Ramu ST. et al, (2023), Immunology
Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study.
Jackson C. et al, (2023), Lancet Respir Med
Novel all-in-one vaccine developed to tackle future coronavirus threats
6 July 2022
Up to $30 million in funding has been announced by the Coalition for Epidemic Preparedness Innovations (CEPI) to bring a new nanoparticle vaccine offering protection against a range of coronaviruses to clinical trial.
Strong cytotoxic T cell responses to an internal viral component are associated with mild COVID-19 disease
1 December 2021
Study from the Dong Group reveals key differences in the adaptive immune responses of patients with mild vs. severe COVID-19, highlighting a potential new vaccine target.
New study reveals role of lymphatic system in bone healing
19 January 2023
Bones were thought to lack lymphatic vessels, but new research from the Kusumbe Group published in Cell not only locates them within bone tissue, but demonstrates their role in bone and blood cell regeneration and reveals changes associated with aging.
Anjali Kusumbe receives the RMS Life Sciences Medal
29 September 2022
The Royal Microscopical Society awards celebrate the best in microscopy, recognising those making a special contribution to microscopy, cytometry and imaging.
Biotech spinout MiroBio acquired by Gilead Sciences for ~£332m
5 August 2022
Co-founded by Simon Davis, MiroBio focuses on developing therapeutics for inflammatory diseases.