Oxford Centre for Diabetes, Endocrinology and Metabolism
OCDEM is a pioneering centre that combines clinical care, research and education in diabetes, endocrine and metabolic diseases. By promoting world-class research, we aim to enhance understanding of these diseases and to accelerate the search for new treatments and cures.
Head of OCDEM
-
David Ray
Professor of Endocrinology, Head of OCDEM, and Co-Director Sir Jules Thorn Sleep and Circadian Neuroscience Institute
History
Read about the beginnings of our centre.
Latest publications
-
Localized GLP-1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
Journal article
Hodson D., (2025), Cell Metabolism
-
Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain
Journal article
Hodson D., (2025), Nature Metabolism
-
The impact of dosage timing for inhaled corticosteroids in asthma: a randomised three-way crossover trial.
Journal article
Wang R. et al, (2025), Thorax
-
Impact of chronic hyperglycaemia on the coronary microcirculation – benefits of targeting IL-36 and diet reversal
Journal article
HODSON D., (2025), Basic Research in Cardiology
OCDEM is one of the largest dedicated research centres in diabetes, endocrinology and metabolism in Europe. Led by Professor David Ray, our work spans the spectrum of basic, translational and patient-orientated research. We are closely integrated with excellent clinical care for patients with diabetes, metabolic and endocrine conditions.
Areas of strength
- Type 2 diabetes including genomics, islet biology and function, novel therapeutics and large-scale clinical trials providing evidence for best practise
- Human integrative metabolic physiology
- Endocrine disorders such as glucocorticoid action, pituitary tumours and calcium homeostasis
Research Facilities
The Oxford BioBank is a resource for medical research to translate early discoveries into benefit for patients.
Funders
Our major funders include AstraZeneca, the European Commission, the Medical Research Council, Merck & Co and the Wellcome Trust.
Latest News
2024 RDM Graduate Citizenship Award Winners
6 February 2025
Study to evaluate treatment of Autonomous Cortisol Secretion
11 December 2024