Oxford Centre for Diabetes, Endocrinology and Metabolism
OCDEM is a pioneering centre that combines clinical care, research and education in diabetes, endocrine and metabolic diseases. By promoting world-class research, we aim to enhance understanding of these diseases and to accelerate the search for new treatments and cures.
Head of OCDEM
Latest Publications
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells.
Ye Y. et al, (2022), Nat Commun, 13
TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes.
Verma M. et al, (2022), Metabolism, 133
Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling
Ariosa-Morejon Y. et al, (2021), eLife, 10
Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice
Li M. et al, (2021), Nature Communications, 12
The Relation Between Adult Weight Gain, Adipocyte Volume And The Metabolic Profile At Middle Age
Verkouter I. et al, (2021), The Journal of Clinical Endocrinology & Metabolism
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.
Viñuela A. et al, (2020), Nat Commun, 11
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
Haythorne E. et al, (2019), Nat Commun, 10
Whole genome sequence analysis identifies a PAX2 mutation to establish a correct diagnosis for a syndromic form of hyperuricemia.
Stevenson M. et al, (2020), Am J Med Genet A
Latest News
2022 RDM Graduate Prize Winners
3 November 2022
This year's winners are Edward Jenkins, Antje Rottner, and Akshay Shah.
Enterprise Associate Interview with Dr Shilpa Nagarajan
27 September 2022
Dr Shilpa Nagarajan is one of the MPLS Enterprise and Innovation Fellows for 2022-23.
Intensive blood glucose control for people with type 2 diabetes when they are first diagnosed reduces diabetic complications and prolongs life
21 September 2022
The study, which tracked volunteers for up to 44 years, showed that the benefits of early intensive blood glucose control can persist for decades.
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