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Research projects

The projects listed below were advertised in the Spring 2025 round of recruitment, which has now closed. New projects will be advertised when we open the next call for fellowship applications, in Spring 2026.

Principal Investigator	Project Title
Prof Jason Lerch, Prof Rogier Mars, Dr Kamila Szulc-Lerch, Dr Giorgio Caratti¹, Dr Chenxi Qin¹	Decoding Neurobiological and Genetic Mechanisms of Obesity Through Big Data and Cross-Species Studies of Brain Structure and Function
Assoc Prof Calliope Dendrou, Prof Mark Coles, Prof Christopher Buckley, Dr Cesar Medina¹	Fibrosis Unmasked: A Metabolic Cell Odyssey Across Tissues and Diseases
Prof Keith Channon, Prof Leanne Hodson, Dr Giorgio Caratti¹	Harnessing environmental redox stresses to identify new metabolic signalling pathways causing Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Dr Filipa Simões, Dr Andrew Lewis, Assoc Prof Chris Toepfer, Dr Julia Krause¹	Human Cardiac Tissue Models to Understand and Target Macrophage-Mitochondrial Communication in Failing Hearts
Dr Gareth Purvis, Prof Keith Channon, Dr Kate M Herum¹	Inflammatory residual risk in CVD
Prof Yimon Aye, Dr Filipa Simões, Dr Luke Haslett¹	Interrogating Precision Metabolite Signaling Actions Promoting Cardiovascular Health & Translation
Prof Nicola Smart, Prof Kim Dora, Assoc Prof Anuj Goel, Dr Nils Rorsman¹	Investigating smooth muscle phenotypic transition in human vascular disease to identify disease-promoting mechanisms, prognostic biomarkers and therapeutic targets
Dr Fergus Imrie, Prof Charlotte Deane, Dr Christos A Nicolaou¹	Machine Learning Approaches for Targeted Fragment Library Design and Experimental Optimisation in Cardiometabolic Drug Development

¹ supervisor from Novo Nordisk or Novo Nordisk Research Centre Oxford