Nuffield Division of Clinical Laboratory Sciences
Our aim is to study the pathology of human disease from the molecular to systems level, and to translate our findings into treatments for human disorders.
Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.
Mettananda S. et al, (2017), Nat Commun, 8
Amatangelo MD. et al, (2017), Blood, 130, 732 - 741
Stein EM. et al, (2017), Blood, 130, 722 - 731
Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature.
Craddock CF. et al, (2017), Clin Cancer Res, 23, 6430 - 6440
Roy NB. et al, (2017), Cochrane Database Syst Rev, 7