DPhil in Medical Sciences
- DPhil in Medical Sciences
DPhil research opportunities 2024
- Cross-talk between adipose tissue and the cardiovascular system in humans: Using Artificial Intelligence to design precision Imaging diagnostics and discover novel therapeutic targets
- Functional coronary artery disease genetics - defining the function of new causal atherosclerosis genes
- Human fat distribution and metabolic disease
- Inflammatory infiltration induces cancer-associated fibroblast differentiation
- Imaging in Preventive Cardiology Research
- Adverse myocardial remodelling in cardiac fibrosis and atrial fibrillation
- Why does turbulent blood flow cause cardiovascular disease?
- Watkins Group – Various projects relating to inherited heart muscle disease
- Iron and Immunity
- De Novo Mutations and Human Disease
- Understanding the principles of gene expression in health and disease.
- Inflammation in p53 mutant myeloproliferative neoplasms
- Developing improved models of normal and malignant blood cell development
- New Immune Therapies For Acute Myeloid Leukaemia (AML) And Myeloid Blood Cancers.
- Building the skull – normal and abnormal development
- Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
- Genomics and Genome Editing
- Therapeutic opportunities emerging from studies of immune checkpoints
- Design of advanced haematopoietic stem cell and T cell therapies
- Non-invasive cardiac metabolism assessment using ultra-high field (7T) MR Spectroscopy
- Understanding how glucagon-like peptide-1 (GLP1) and gastric inhibitory polypeptide (GIP) receptors contribute to metabolism in complex tissues
- Elucidating the role of disease modifying gene variants in inherited cardiomyopathies using induced pluripotent stem cell derived cardiomyocytes and CRISPR/Cas-9
- Hyde Group - Airway Gene Therapy - Engineering Lentiviral Vectors for Lung Cell-Specific Targeting
- Characterising spatial tissue niches in human immune system development and disease using computational biology, machine learning and multi-omics approaches
- Applications of multi-omics and AI to decode T cell recognition code in time and space
- Kini Group - A network approach to identifying novel genes causing neurodevelopmental disorders- The SATB pathway
- Imaging-based analysis of signalling pathways triggered by immune checkpoint receptors
- Generating extracellular vesicles for therapeutic Immunomodulation and building tools to determine their diagnostic potential.
- Development and Application of Hyperpolarized Magnetic Resonance Imaging in the Study of the Diseased Heart
- Homologous recombination in genome maintenance and cancer prevention
- Impact of endogenous DNA damage and repair in early haematopoiesis
- Non-invasive tests for the prediction of clinical outcomes in people with metabolic dysfunction associated steatotic liver disease
- Development and combination of advanced neuroimaging to understand functional changes in Multiple Sclerosis
- How do protein making factories prevent cardiovascular disease?
- Development of genetic therapies for cardiomyopathy: creating an evidence base for ethical and clinical implementation.
- Advanced early detection of lytic bone disease using multi-modal computational analysis of bone marrow biopsies and skeletal imaging
- Occult hepatitis B virus infection (OBI) in people who donate blood: virology, immunology and liver health (OPAL)
- Characterising Human Intestinal Development and Dysregulation in Childhood Diseases
- Single Cell Biology, Molecular Mechanisms And Genetics of Transformation of Clonal Haemopoiesis to Myeloid Blood Cancer (MDS and AML)
- Developing new echocardiography diagnostics with AI
- How to apply
- Funding Options
- Meet the team
Career Paths of Former Students
- Associate Professor - Universiti Putra Malaysia
- Freelance Copy Editor
- Wellcome Trust Research Fellow - Kennedy Institute, University of Oxford
- Sir Henry Wellcome Postdoctoral Fellow - Stanford University
- Senior Scientist - Immunocore
- Postdoctoral Fellow - Walter & Eliza Hall Institute of Medical Research
- Assistant Head Teacher - West London Free School
- Professor of Cardiovascular Medicine - Queen Mary University London, Barts & The London School of Medicine and Dentistry
- University Research Lecturer & British Heart Foundation Research Fellow - Cardiovascular Medicine, RDM, University of Oxford
- Senior Policy Manager - Research Councils UK (RCUK)
- Skills and Training
Our DPhil research programme trains the next generation of leading scientists.
Our DPhil (Doctor of Philosophy) degree in Medical Sciences covers the whole span of the department’s research. In keeping with our focus on translational research, we welcome applications from both basic scientists and clinicians.
You will be admitted directly onto a research project with a specific Principal Investigator, who will act as your supervisor, and will be one of RDM's world-leading scientists. Students are asked to nominate up to three supervisors from the list of research opportunities. You will be expected to play an active role in shaping your project over the course of the DPhil. Our students are a valuable part of the department and we encourage them to be involved with the scientific and social life of the department at all levels.
Most students also have one or more formal co-supervisors, who can provide additional scientific advice on their specialist areas and who will offer another viewpoint on the student’s project. Together, they form the specialised team that will advise you on your academic progress. If you don’t have a formal co-supervisor, you will have a nominated secondary supervisor who you can always ask for advice, but who will not be actively involved with your project on a day-to-day basis.
As well as your supervisor, you will have the support of a Graduate Advisor, the Director of Graduate Studies and the Graduate Studies Administrator. All activity relating to graduate students within the department is overseen by the Graduate Studies Committee.
In addition, the department has graduate student representatives; two of which sit on the Graduate Studies Committee. They act as the point of contact for the students and ensure that any concerns amongst students can be heard by the department and acted upon.
Key Dates for October 2024 Entry
The Radcliffe Department of Medicine has fully-funded 4-year PhD (DPhil) studentships, to start in October 2024. These are open to outstanding students of any nationality who wish to pursue a career in experimental and/or computational biology in a range of areas including cardiovascular sciences, diabetes and endocrinology, immunology, haematology, and developmental biology.
You can find full details on the application process in the University’s application guide.
How to apply
To apply for a place on the DPhil in Medical Sciences you will need to submit an application using the online application form.