Fellows' Publications

Insulin signalling requires glucose to promote lipid anabolism in adipocytes

Journal article

Krycer JR. et al, (2020), Journal of Biological Chemistry, jbc.RA120.014907 - jbc.RA120.014907

Fatty acid oxidation is an adaptive survival pathway induced in prostate tumors by heat shock protein 90 inhibition.

Journal article

Nassar ZD. et al, (2020), Mol Cancer Res

Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity.

Journal article

Thomas CW. et al, (2020), Elife, 9

Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis.

Journal article

Gunn PJ. et al, (2020), Physiol Rep, 8

Inpatient hypoglycaemia: understanding who is at risk.

Journal article

Ruan Y. et al, (2020), Diabetologia, 63, 1299 - 1304

Predicting the Risk of Inpatient Hypoglycemia With Machine Learning Using Electronic Health Records.

Journal article

Ruan Y. et al, (2020), Diabetes Care, 43, 1504 - 1511

Sleep and ageing: from human studies to rodent models.

Journal article

McKillop LE. and Vyazovskiy VV., (2020), Curr Opin Physiol, 15, 210 - 216

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet.

Journal article

Kellard JA. et al, (2020), Mol Metab, 40

PYY, a Therapeutic Option for Type 2 Diabetes?

Journal article

Guida C. and Ramracheya R., (2020), Clinical Medicine Insights: Endocrinology and Diabetes, 13

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.

Journal article

Vergari E. et al, (2020), Nat Metab, 2, 32 - 40

Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states.

Journal article

Liu J. et al, (2019), Biochim Biophys Acta Mol Cell Biol Lipids, 1864

A role for placental kisspeptin in β cell adaptation to pregnancy

Journal article

Bowe JE. et al, (2019), JCI Insight, 4

Sleep homeostasis reflects temporally integrated local cortical neuronal activity

Journal article

Thomas CW. et al, (2019)

Sleep homeostasis during daytime food entrainment in mice

Journal article

Northeast R. et al, (2019), SLEEP

The effect of metformin on hepatic fatty acid partitioning; an investigation using human in vivo and in vitro models

Conference paper

Green C. et al, (2019), JOURNAL OF HEPATOLOGY, 70, E794 - E795

SGLT2 inhibition does not reduce hepatic steatosis in overweight, insulin resistant patients without type 2 diabetes

Conference paper

Marjot T. et al, (2019), JOURNAL OF HEPATOLOGY, 70, E68 - E68

Importance of inpatient hypoglycaemia: impact, prediction and prevention.

Journal article

Ruan Y. et al, (2019), Diabet Med, 36, 434 - 443

PYY plays a key role in the resolution of diabetes following bariatric surgery in humans.

Journal article

Guida C. et al, (2019), EBioMedicine, 40, 67 - 76

Mapping tissue water T1 in the liver using the MOLLI T1 method in the presence of fat, iron and B0 inhomogeneity.

Journal article

Mozes FE. et al, (2019), NMR Biomed, 32

A multidisciplinary approach to the management of NAFLD is associated with improvement in markers of liver and cardio-metabolic health

Journal article

Moolla A. et al, (2019), Frontline Gastroenterology

Sleep- and Wake-Like States in Small Networks In Vivo and In Vitro.

Journal article

McKillop LE. and Vyazovskiy VV., (2018), Handb Exp Pharmacol

Liver biochemical abnormalities in Turner syndrome: A comprehensive characterization of an adult population.

Journal article

Calanchini M. et al, (2018), Clin Endocrinol (Oxf), 89, 667 - 676

Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders.

Journal article

Ang G. et al, (2018), Transl Psychiatry, 8

Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain

Journal article

Ved N. et al, (2018), The Journal of Physiology, 596, 3675 - 3693

Cortical region-specific sleep homeostasis in mice: effects of time of day and waking experience.

Journal article

Guillaumin MCC. et al, (2018), Sleep, 41

Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators.

Journal article

Bates DO. et al, (2018), Compr Physiol, 8, 955 - 979

Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice.

Journal article

Kuipers EN. et al, (2018), Int J Mol Sci, 19

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets.

Journal article

Briant LJB. et al, (2018), Cell Rep, 23, 3300 - 3311

MANAGING NAFLD VIA A MULTIDISCIPLINARY CLINIC APPROACH IMPROVES LIVER HEALTH AND IS COST EFFECTIVE

Conference paper

Cobbold J. et al, (2018), GUT, 67, A109 - A110

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.

Journal article

Hamilton A. et al, (2018), Diabetes, 67, 1128 - 1139

Effects of Aging on Cortical Neural Dynamics and Local Sleep Homeostasis in Mice.

Journal article

McKillop LE. et al, (2018), J Neurosci, 38, 3911 - 3928

Bolusing frequency and amount impacts glucose control during hybrid closed-loop

Journal article

Bally L. et al, (2018), Diabetic Medicine, 35, 347 - 351

Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY.

Journal article

Guida C. et al, (2018), Diabetes Obes Metab, 20, 571 - 581

The GPR 120 agonist TUG ‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

Journal article

Schilperoort M. et al, (2018), EMBO Molecular Medicine, 10

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement

Journal article

van Dam AD. et al, (2018), International Journal of Obesity, 42, 260 - 269

Prevalence and severity of non-alcoholic fatty liver disease are underestimated in clinical practice: impact of a dedicated screening approach at a large university teaching hospital.

Journal article

Marjot T. et al, (2018), Diabet Med, 35, 89 - 98

THE CORTICAL NEURAL ACTIVITY OF MICE IS RESILIENT TO AGEING, DESPITE MARKED DISRUPTION IN GLOBAL SLEEP

Conference paper

McKillop LE. et al, (2017), SLEEP MEDICINE, 40, E218 - E219

South Asian men have lower expression of IFN signalling genes in white adipose tissue and skeletal muscle compared with white men

Journal article

van Dam AD. et al, (2017), Diabetologia, 60, 2525 - 2528

Targeting white, brown and perivascular adipose tissue in atherosclerosis development

Journal article

van Dam AD. et al, (2017), European Journal of Pharmacology, 816, 82 - 92

l-phenylalanine modulates gut hormone release and glucose tolerance, and suppresses food intake through the calcium-sensing receptor in rodents.

Journal article

Alamshah A. et al, (2017), Int J Obes (Lond), 41, 1693 - 1701

Faster insulin action is associated with improved glycaemic outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes

Journal article

Ruan Y. et al, (2017), Diabetes, Obesity and Metabolism, 19, 1485 - 1489

Lorcaserin improves glycemic control via a melanocortin neurocircuit

Journal article

Burke LK. et al, (2017), Molecular Metabolism, 6, 1092 - 1102

Cover Image, Volume 19, Issue 10

Journal article

Ruan Y. et al, (2017), Diabetes, Obesity and Metabolism, 19, i - i

The Role of PYY in Pancreatic Islet Physiology and Surgical Control of Diabetes.

Journal article

Guida C. et al, (2017), Trends Endocrinol Metab, 28, 626 - 636

Modeling Day-to-Day Variability of Glucose–Insulin Regulation Over 12-Week Home Use of Closed-Loop Insulin Delivery

Journal article

Ruan Y. et al, (2017), IEEE Transactions on Biomedical Engineering, 64, 1412 - 1419

Vascular endothelial growth factor-A 165 b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina

Journal article

Ved N. et al, (2017), Clinical Science, 131, 1225 - 1243

The role of PYY in pancreatic islet physiology and surgical control of diabetes

Journal article

Guida C. et al, (2017), Trends in Endocrinology and Metabolism

Sensor Life and Overnight Closed Loop: A Randomized Clinical Trial

Journal article

Tauschmann M. et al, (2017), Journal of Diabetes Science and Technology, 11, 513 - 521

Lack of skeletal muscle IL-6 influences hepatic glucose metabolism in mice during prolonged exercise.

Journal article

Bertholdt L. et al, (2017), Am J Physiol Regul Integr Comp Physiol, 312, R626 - R636

Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

Journal article

Nagarajan SR. et al, (2017), PLOS ONE, 12, e0174431 - e0174431

Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial

Journal article

Thabit H. et al, (2017), The Lancet Diabetes & Endocrinology, 5, 117 - 124

Skeletal muscle IL-6 regulates muscle substrate utilization and adipose tissue metabolism during recovery from an acute bout of exercise.

Journal article

Knudsen JG. et al, (2017), PLoS One, 12

GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.

Journal article

Veprik A. et al, (2016), FASEB J, 30, 3860 - 3869

Stereotypic wheel running decreases cortical activity in mice.

Journal article

Fisher SP. et al, (2016), Nat Commun, 7

High risk populations: Attitudes to NAFLD among Diabetologists

Conference paper

Marjot T. et al, (2016), HEPATOLOGY, 64, 557A - 557A

Dynamics of cortical network activity in non-rapid eye movement sleep in early and late adulthood mice

Conference paper

McKillop LE. et al, (2016), JOURNAL OF SLEEP RESEARCH, 25, 98 - 98

Serum metabolomics profiles in response to n-3 fatty acids in Chinese patients with type 2 diabetes: a double-blind randomised controlled trial

Journal article

Zheng J-S. et al, (2016), Scientific Reports, 6

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice

Journal article

van Dam AD. et al, (2016), Atherosclerosis, 251, 6 - 14

Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes

Journal article

Ruan Y. et al, (2016), Diabetes Care, 39, 830 - 832

Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training.

Journal article

Knudsen JG. et al, (2016), Physiol Rep, 4

L-arginine promotes gut hormone release and reduces food intake in rodents.

Journal article

Alamshah A. et al, (2016), Diabetes Obes Metab, 18, 508 - 518

Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise.

Journal article

Gudiksen A. et al, (2016), PLoS One, 11

Imaging Bone-Cartilage Interactions in Osteoarthritis Using [18F]-NaF PET-MRI.

Journal article

Savic D. et al, (2016), Mol Imaging, 15, 1 - 12

Modeling predicts a connection between sinus vortex effects and aortic compliance

Journal article

Aboelkassem Y. et al, (2016), Journal of Theoretical Biology, 389, 306 - 309

Non-invasive Markers of Liver Fibrosis: Adjuncts or Alternatives to Liver Biopsy?

Journal article

Chin JL. et al, (2016), Front Pharmacol, 7

Modelling endogenous insulin concentration in type 2 diabetes during closed-loop insulin delivery

Journal article

Ruan Y. et al, (2015), BioMedical Engineering OnLine, 14

Cartilage T 1ρ and T 2 relaxation times: longitudinal reproducibility and variations using different coils, MR systems and sites

Journal article

Li X. et al, (2015), Osteoarthritis and Cartilage, 23, 2214 - 2223

Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells

Journal article

Wang Y. et al, (2015), Hepatology, 62, 1710 - 1722

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration

Journal article

Hulse RP. et al, (2015), Clinical Science, 129, 741 - 756

Regulation of brown fat by AMP-activated protein kinase

Journal article

van Dam AD. et al, (2015), Trends in Molecular Medicine, 21, 571 - 579

Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training.

Journal article

Knudsen JG. et al, (2015), Obesity (Silver Spring), 23, 1616 - 1624

Exercise-induced regulation of key factors in substrate choice and gluconeogenesis in mouse liver.

Journal article

Knudsen JG. et al, (2015), Mol Cell Biochem, 403, 209 - 217

Salsalate Activates Brown Adipose Tissue in Mice

Journal article

van Dam AD. et al, (2015), Diabetes, 64, 1544 - 1554

Pharmacokinetics of diluted (U20) insulin aspart compared with standard (U100) in children aged 3–6 years with type 1 diabetes during closed-loop insulin delivery: a randomised clinical trial

Journal article

Ruan Y. et al, (2015), Diabetologia, 58, 687 - 690

Mathematical modeling of aortic valve dynamics during systole

Journal article

Aboelkassem Y. et al, (2015), Journal of Theoretical Biology, 365, 280 - 288

Assessing Biological Response to Bevacizumab Using 18F-Fluoromisonidazole PET/MR Imaging in a Patient with Recurrent Anaplastic Astrocytoma

Journal article

Barajas RF. et al, (2015), Case Reports in Radiology, 2015, 1 - 4

Complications of diabetes: progress, but significant challenges ahead.

Journal article

Chowdhury TA. et al, (2014), Ann Transl Med, 2

Pharmacokinetics of insulin lispro in type 2 diabetes during closed-loop insulin delivery

Journal article

Ruan Y. et al, (2014), Computer Methods and Programs in Biomedicine, 117, 298 - 307

The effect of magnetic field on positron range and spatial resolution in an integrated whole-body time-of-flight PET/MRI system

Journal article

Shih-ying Huang None. et al, (2014), 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

Effects of IL-6 on pyruvate dehydrogenase regulation in mouse skeletal muscle.

Journal article

Biensø RS. et al, (2014), Pflugers Arch, 466, 1647 - 1657

Long-term history and immediate preceding state affect EEG slow wave characteristics at NREM sleep onset in C57BL/6 mice.

Journal article

Cui N. et al, (2014), Arch Ital Biol, 152, 156 - 168

Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue.

Journal article

Knudsen JG. et al, (2014), PLoS One, 9

Fellows' Publications

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