Fellows' Publications
Latest publications
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Continuous and non-invasive thermography of mouse skin accurately describes core body temperature patterns, but not absolute core temperature.
Journal article
van der Vinne V. et al, (2020), Sci Rep, 10
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Insulin signalling requires glucose to promote lipid anabolism in adipocytes
Journal article
Krycer JR. et al, (2020), Journal of Biological Chemistry, jbc.RA120.014907 - jbc.RA120.014907
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Fatty acid oxidation is an adaptive survival pathway induced in prostate tumors by heat shock protein 90 inhibition.
Journal article
Nassar ZD. et al, (2020), Mol Cancer Res
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Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity.
Journal article
Thomas CW. et al, (2020), Elife, 9
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Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis.
Journal article
Gunn PJ. et al, (2020), Physiol Rep, 8
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Inpatient hypoglycaemia: understanding who is at risk.
Journal article
Ruan Y. et al, (2020), Diabetologia, 63, 1299 - 1304
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Predicting the Risk of Inpatient Hypoglycemia With Machine Learning Using Electronic Health Records.
Journal article
Ruan Y. et al, (2020), Diabetes Care, 43, 1504 - 1511
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Sleep and ageing: from human studies to rodent models.
Journal article
McKillop LE. and Vyazovskiy VV., (2020), Curr Opin Physiol, 15, 210 - 216
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Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet.
Journal article
Kellard JA. et al, (2020), Mol Metab, 40
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PYY, a Therapeutic Option for Type 2 Diabetes?
Journal article
Guida C. and Ramracheya R., (2020), Clinical Medicine Insights: Endocrinology and Diabetes, 13
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Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.
Journal article
Vergari E. et al, (2020), Nat Metab, 2, 32 - 40
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Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states.
Journal article
Liu J. et al, (2019), Biochim Biophys Acta Mol Cell Biol Lipids, 1864
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A role for placental kisspeptin in β cell adaptation to pregnancy
Journal article
Bowe JE. et al, (2019), JCI Insight, 4
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Sleep homeostasis reflects temporally integrated local cortical neuronal activity
Journal article
Thomas CW. et al, (2019)
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Sleep homeostasis during daytime food entrainment in mice
Journal article
Northeast R. et al, (2019), SLEEP
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The effect of metformin on hepatic fatty acid partitioning; an investigation using human in vivo and in vitro models
Conference paper
Green C. et al, (2019), JOURNAL OF HEPATOLOGY, 70, E794 - E795
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SGLT2 inhibition does not reduce hepatic steatosis in overweight, insulin resistant patients without type 2 diabetes
Conference paper
Marjot T. et al, (2019), JOURNAL OF HEPATOLOGY, 70, E68 - E68
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Importance of inpatient hypoglycaemia: impact, prediction and prevention.
Journal article
Ruan Y. et al, (2019), Diabet Med, 36, 434 - 443
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PYY plays a key role in the resolution of diabetes following bariatric surgery in humans.
Journal article
Guida C. et al, (2019), EBioMedicine, 40, 67 - 76
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Mapping tissue water T1 in the liver using the MOLLI T1 method in the presence of fat, iron and B0 inhomogeneity.
Journal article
Mozes FE. et al, (2019), NMR Biomed, 32
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A multidisciplinary approach to the management of NAFLD is associated with improvement in markers of liver and cardio-metabolic health
Journal article
Moolla A. et al, (2019), Frontline Gastroenterology
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Sleep- and Wake-Like States in Small Networks In Vivo and In Vitro.
Journal article
McKillop LE. and Vyazovskiy VV., (2018), Handb Exp Pharmacol
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Liver biochemical abnormalities in Turner syndrome: A comprehensive characterization of an adult population.
Journal article
Calanchini M. et al, (2018), Clin Endocrinol (Oxf), 89, 667 - 676
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Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders.
Journal article
Ang G. et al, (2018), Transl Psychiatry, 8
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Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain
Journal article
Ved N. et al, (2018), The Journal of Physiology, 596, 3675 - 3693
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Cortical region-specific sleep homeostasis in mice: effects of time of day and waking experience.
Journal article
Guillaumin MCC. et al, (2018), Sleep, 41
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Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators.
Journal article
Bates DO. et al, (2018), Compr Physiol, 8, 955 - 979
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Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice.
Journal article
Kuipers EN. et al, (2018), Int J Mol Sci, 19
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CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets.
Journal article
Briant LJB. et al, (2018), Cell Rep, 23, 3300 - 3311
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Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.
Journal article
Hamilton A. et al, (2018), Diabetes, 67, 1128 - 1139
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Effects of Aging on Cortical Neural Dynamics and Local Sleep Homeostasis in Mice.
Journal article
McKillop LE. et al, (2018), J Neurosci, 38, 3911 - 3928
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Bolusing frequency and amount impacts glucose control during hybrid closed-loop
Journal article
Bally L. et al, (2018), Diabetic Medicine, 35, 347 - 351
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Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY.
Journal article
Guida C. et al, (2018), Diabetes Obes Metab, 20, 571 - 581
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The
GPR
120 agonist
TUG
‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat
Journal article
Schilperoort M. et al, (2018), EMBO Molecular Medicine, 10
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IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement
Journal article
van Dam AD. et al, (2018), International Journal of Obesity, 42, 260 - 269
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Prevalence and severity of non-alcoholic fatty liver disease are underestimated in clinical practice: impact of a dedicated screening approach at a large university teaching hospital.
Journal article
Marjot T. et al, (2018), Diabet Med, 35, 89 - 98
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THE CORTICAL NEURAL ACTIVITY OF MICE IS RESILIENT TO AGEING, DESPITE MARKED DISRUPTION IN GLOBAL SLEEP
Conference paper
McKillop LE. et al, (2017), SLEEP MEDICINE, 40, E218 - E219
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South Asian men have lower expression of IFN signalling genes in white adipose tissue and skeletal muscle compared with white men
Journal article
van Dam AD. et al, (2017), Diabetologia, 60, 2525 - 2528
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Targeting white, brown and perivascular adipose tissue in atherosclerosis development
Journal article
van Dam AD. et al, (2017), European Journal of Pharmacology, 816, 82 - 92
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Faster insulin action is associated with improved glycaemic outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes
Journal article
Ruan Y. et al, (2017), Diabetes, Obesity and Metabolism, 19, 1485 - 1489
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Lorcaserin improves glycemic control via a melanocortin neurocircuit
Journal article
Burke LK. et al, (2017), Molecular Metabolism, 6, 1092 - 1102
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Cover Image, Volume 19, Issue 10
Journal article
Ruan Y. et al, (2017), Diabetes, Obesity and Metabolism, 19, i - i
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The Role of PYY in Pancreatic Islet Physiology and Surgical Control of Diabetes.
Journal article
Guida C. et al, (2017), Trends Endocrinol Metab, 28, 626 - 636
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Modeling Day-to-Day Variability of Glucose–Insulin Regulation Over 12-Week Home Use of Closed-Loop Insulin Delivery
Journal article
Ruan Y. et al, (2017), IEEE Transactions on Biomedical Engineering, 64, 1412 - 1419
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Vascular endothelial growth factor-A
165
b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina
Journal article
Ved N. et al, (2017), Clinical Science, 131, 1225 - 1243
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The role of PYY in pancreatic islet physiology and surgical control of diabetes
Journal article
Guida C. et al, (2017), Trends in Endocrinology and Metabolism
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Sensor Life and Overnight Closed Loop: A Randomized Clinical Trial
Journal article
Tauschmann M. et al, (2017), Journal of Diabetes Science and Technology, 11, 513 - 521
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Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver
Journal article
Nagarajan SR. et al, (2017), PLOS ONE, 12, e0174431 - e0174431
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Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial
Journal article
Thabit H. et al, (2017), The Lancet Diabetes & Endocrinology, 5, 117 - 124
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GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.
Journal article
Veprik A. et al, (2016), FASEB J, 30, 3860 - 3869
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Stereotypic wheel running decreases cortical activity in mice.
Journal article
Fisher SP. et al, (2016), Nat Commun, 7
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Dynamics of cortical network activity in non-rapid eye movement sleep in early and late adulthood mice
Conference paper
McKillop LE. et al, (2016), JOURNAL OF SLEEP RESEARCH, 25, 98 - 98
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Serum metabolomics profiles in response to n-3 fatty acids in Chinese patients with type 2 diabetes: a double-blind randomised controlled trial
Journal article
Zheng J-S. et al, (2016), Scientific Reports, 6
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BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice
Journal article
van Dam AD. et al, (2016), Atherosclerosis, 251, 6 - 14
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Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes
Journal article
Ruan Y. et al, (2016), Diabetes Care, 39, 830 - 832
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Imaging Bone-Cartilage Interactions in Osteoarthritis Using [18F]-NaF PET-MRI.
Journal article
Savic D. et al, (2016), Mol Imaging, 15, 1 - 12
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Modeling predicts a connection between sinus vortex effects and aortic compliance
Journal article
Aboelkassem Y. et al, (2016), Journal of Theoretical Biology, 389, 306 - 309
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Modelling endogenous insulin concentration in type 2 diabetes during closed-loop insulin delivery
Journal article
Ruan Y. et al, (2015), BioMedical Engineering OnLine, 14
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Cartilage T 1ρ and T 2 relaxation times: longitudinal reproducibility and variations using different coils, MR systems and sites
Journal article
Li X. et al, (2015), Osteoarthritis and Cartilage, 23, 2214 - 2223
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Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells
Journal article
Wang Y. et al, (2015), Hepatology, 62, 1710 - 1722
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Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration
Journal article
Hulse RP. et al, (2015), Clinical Science, 129, 741 - 756
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Regulation of brown fat by AMP-activated protein kinase
Journal article
van Dam AD. et al, (2015), Trends in Molecular Medicine, 21, 571 - 579
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Salsalate Activates Brown Adipose Tissue in Mice
Journal article
van Dam AD. et al, (2015), Diabetes, 64, 1544 - 1554
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Pharmacokinetics of diluted (U20) insulin aspart compared with standard (U100) in children aged 3–6 years with type 1 diabetes during closed-loop insulin delivery: a randomised clinical trial
Journal article
Ruan Y. et al, (2015), Diabetologia, 58, 687 - 690
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Mathematical modeling of aortic valve dynamics during systole
Journal article
Aboelkassem Y. et al, (2015), Journal of Theoretical Biology, 365, 280 - 288
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Assessing Biological Response to Bevacizumab Using 18F-Fluoromisonidazole PET/MR Imaging in a Patient with Recurrent Anaplastic Astrocytoma
Journal article
Barajas RF. et al, (2015), Case Reports in Radiology, 2015, 1 - 4
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Pharmacokinetics of insulin lispro in type 2 diabetes during closed-loop insulin delivery
Journal article
Ruan Y. et al, (2014), Computer Methods and Programs in Biomedicine, 117, 298 - 307
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The effect of magnetic field on positron range and spatial resolution in an integrated whole-body time-of-flight PET/MRI system
Journal article
Shih-ying Huang None. et al, (2014), 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
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Long-term history and immediate preceding state affect EEG slow wave characteristics at NREM sleep onset in C57BL/6 mice.
Journal article
Cui N. et al, (2014), Arch Ital Biol, 152, 156 - 168