Fellows' Publications

Developing a metabolic clearance rate framework as a translational analysis approach for hyperpolarized 13C magnetic resonance imaging.

Journal article

Grist JT. et al, (2023), Sci Rep, 13

Reversible pH-responsive MRI contrast with paramagnetic polymer micelles.

Journal article

Ellis CM. et al, (2023), Chem Commun (Camb)

Cardiometabolic risk factors vary with age differently in females and males

Journal article

Miller JJ. and Heather LC., (2022), Nature Cardiovascular Research

Direct observation of the molecular mechanism underlying protein polymerization.

Journal article

Hundt N. et al, (2022), Sci Adv, 8

Assessing the effect of anesthetic gas mixtures on hyperpolarized 13 C pyruvate metabolism in the rat brain.

Journal article

Healicon R. et al, (2022), Magn Reson Med, 88, 1324 - 1332

Functional and Metabolic Imaging in Heart Failure with Preserved Ejection Fraction: Promises, Challenges, and Clinical Utility.

Journal article

Burrage MK. et al, (2022), Cardiovasc Drugs Ther

A neuroimmunometabolic view on the cephalic phase of insulin release.

Journal article

Sarker G. and Domingos AI., (2022), Cell Metab, 34, 940 - 942

Glycogen-autophagy: Molecular machinery and cellular mechanisms of glycophagy.

Journal article

Koutsifeli P. et al, (2022), J Biol Chem, 298

Concentration-dependent effects of dichloroacetate in type 2 diabetic hearts assessed by hyperpolarized [1-13 C]-pyruvate magnetic resonance imaging.

Journal article

Hansen ESS. et al, (2022), NMR Biomed, 35

Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.

Journal article

Hazlehurst JM. et al, (2022), Metabol Open, 14

The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation.

Journal article

Dearlove DJ. et al, (2022), Physiol Rep, 10

Promoting high T2 contrast in Dy-doped MSNs through Curie effects.

Journal article

Ellis CM. et al, (2022), J Mater Chem B, 10, 302 - 305

A phase 2a trial investigating ninerafaxstat - a novel cardiac mitotrope for the treatment of diabetic cardiomyopathy (IMPROVE-DiCE)

Conference paper

Hundertmark M. et al, (2022), EUROPEAN HEART JOURNAL, 43, 246 - 246

Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH.

Journal article

Wilson AD. et al, (2021), Cardiovasc Res

Energetic Basis for Exercise-Induced Pulmonary Congestion in Heart Failure With Preserved Ejection Fraction.

Journal article

Burrage MK. et al, (2021), Circulation, 144, 1664 - 1678

Intentional Weight Loss as a Novel Treatment for Heart Failure with Preserved Ejection Fraction

Conference paper

Hundertmark MJ. et al, (2021), CIRCULATION, 144

Myocardial Energetic Impairment is the Basis for Reduced Cardiac Reserve and Exercise-Induced Pulmonary Congestion in Heart Failure With Preserved Ejection Fraction: Insights From Novel Cardiopulmonary Magnetic Resonance Imaging

Conference paper

Burrage MK. et al, (2021), CIRCULATION, 144

Frequency drift in MR spectroscopy at 3T.

Journal article

Hui SCN. et al, (2021), Neuroimage, 241

A simple, open and extensible gating Control unit for cardiac and respiratory synchronisation control in small animal MRI and demonstration of its robust performance in steady-state maintained CINE-MRI.

Journal article

Gilchrist S. et al, (2021), Magn Reson Imaging, 81, 1 - 9

Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia.

Journal article

Kerr M. et al, (2021), FASEB J, 35

Maternal iron deficiency perturbs embryonic cardiovascular development in mice.

Journal article

Kalisch-Smith JI. et al, (2021), Nature communications, 12

Maternal iron deficiency perturbs embryonic cardiovascular development in mice.

Journal article

Kalisch-Smith JI. et al, (2021), Nat Commun, 12

Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro

Journal article

Daniels LJ. et al, (2021), Nutrition & Diabetes, 11

Proof-of-Principle Demonstration of Direct Metabolic Imaging Following Myocardial Infarction Using Hyperpolarized 13C CMR.

Journal article

Apps A. et al, (2021), JACC Cardiovasc Imaging, 14, 1285 - 1288

Rapid, B 1 -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

Journal article

Miller JJ. et al, (2021), Magn Reson Med, 85, 2978 - 2991

Association of Left Ventricular Global Longitudinal Strain With Cardiac Amyloid Load in Light Chain Amyloidosis

Journal article

Kim D. et al, (2021), JACC: Cardiovascular Imaging, 14, 1283 - 1285

IMPAIRED MYOCARDIAL ENERGETICS AS THE BASIS FOR EXERCISE-INDUCED PULMONARY CONGESTION IN HEART FAILURE WITH PRESERVED EJECTION FRACTION

Conference paper

Burrage MK. et al, (2021), HEART, 107, A177 - A177

Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR.

Journal article

Marco-Rius I. et al, (2021), MAGMA, 34, 49 - 56

A 3D hybrid-shot spiral sequence for hyperpolarized 13 C imaging.

Journal article

Tyler A. et al, (2021), Magn Reson Med, 85, 790 - 801

Fructose Metabolism and Cardiac Metabolic Stress.

Journal article

Annandale M. et al, (2021), Front Pharmacol, 12

Magnetic Resonance pH Imaging in Stroke - Combining the Old With the New.

Journal article

Larkin JR. et al, (2021), Front Physiol, 12

HP acquisition methods: pulse sequences, reconstruction, and RF coils

Chapter

Gordon JW. and Miller JJ., (2021), Advances in Magnetic Resonance Technology and Applications, 49 - 74

Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics.

Journal article

Timm KN. et al, (2021), Front Physiol, 12

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.

Journal article

Timm KN. et al, (2020), Commun Biol, 3

Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.

Journal article

Watson WD. et al, (2020), FASEB J, 34, 14878 - 14891

Effects of contrast agents on relaxation properties of 31P metabolites.

Journal article

Valkovič L. et al, (2020), Magn Reson Med

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol.

Journal article

Kerr M. et al, (2020), JCI Insight, 5

Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis.

Journal article

Gunn PJ. et al, (2020), Physiol Rep, 8

Cardiac Energetics in Patients With Aortic Stenosis and Preserved Versus Reduced Ejection Fraction.

Journal article

Peterzan MA. et al, (2020), Circulation, 141, 1971 - 1985

Use of cardiac magnetic resonance to detect changes in metabolism in heart failure.

Journal article

Watson WD. et al, (2020), Cardiovasc Diagn Ther, 10, 583 - 597

Hyperpolarized 13C MRI: A novel approach for probing cerebral metabolism in health and neurological disease.

Journal article

Grist JT. et al, (2020), J Cereb Blood Flow Metab, 40, 1137 - 1147

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet.

Journal article

Kellard JA. et al, (2020), Mol Metab, 40

Noninvasive In Vivo Assessment of Cardiac Metabolism in the Healthy and Diabetic Human Heart Using Hyperpolarized 13C MRI.

Journal article

Rider OJ. et al, (2020), Circ Res, 126, 725 - 736

PYY, a Therapeutic Option for Type 2 Diabetes?

Journal article

Guida C. and Ramracheya R., (2020), Clinical Medicine Insights: Endocrinology and Diabetes, 13

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.

Journal article

Vergari E. et al, (2020), Nat Metab, 2, 32 - 40

Conditionally immortalized brown preadipocytes can switch between proliferative and differentiated states.

Journal article

Liu J. et al, (2019), Biochim Biophys Acta Mol Cell Biol Lipids, 1864

A role for placental kisspeptin in β cell adaptation to pregnancy

Journal article

Bowe JE. et al, (2019), JCI Insight, 4

A multidisciplinary approach to the management of NAFLD is associated with improvement in markers of liver and cardio-metabolic health.

Journal article

Moolla A. et al, (2019), Frontline Gastroenterol, 10, 337 - 346

Water gated contrast switching with polymer-silica hybrid nanoparticles.

Journal article

Pellico J. et al, (2019), Chem Commun (Camb), 55, 8540 - 8543

The effect of metformin on hepatic fatty acid partitioning; an investigation using human in vivo and in vitro models

Conference paper

Green C. et al, (2019), JOURNAL OF HEPATOLOGY, 70, E794 - E795

SGLT2 inhibition does not reduce hepatic steatosis in overweight, insulin resistant patients without type 2 diabetes

Conference paper

Marjot T. et al, (2019), JOURNAL OF HEPATOLOGY, 70, E68 - E68

PYY plays a key role in the resolution of diabetes following bariatric surgery in humans.

Journal article

Guida C. et al, (2019), EBioMedicine, 40, 67 - 76

Mapping tissue water T1 in the liver using the MOLLI T1 method in the presence of fat, iron and B0 inhomogeneity.

Journal article

Mozes FE. et al, (2019), NMR Biomed, 32

Large expert-curated database for benchmarking document similarity detection in biomedical literature search.

Journal article

Brown P. et al, (2019), Database (Oxford), 2019

Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.

Journal article

Sun W. et al, (2018), Nature medicine, 24

Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.

Journal article

Sun W. et al, (2018), Nature medicine, 24

Liver biochemical abnormalities in Turner syndrome: A comprehensive characterization of an adult population.

Journal article

Calanchini M. et al, (2018), Clin Endocrinol (Oxf), 89, 667 - 676

Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis.

Journal article

Miller JJ. et al, (2018), JACC Cardiovasc Imaging, 11, 1594 - 1606

13C Pyruvate Transport Across the Blood-Brain Barrier in Preclinical Hyperpolarised MRI.

Journal article

Miller JJ. et al, (2018), Sci Rep, 8

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS.

Journal article

Timm KN. et al, (2018), NMR Biomed, 31

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets.

Journal article

Briant LJB. et al, (2018), Cell Rep, 23, 3300 - 3311

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.

Journal article

Hamilton A. et al, (2018), Diabetes, 67, 1128 - 1139

Cardiac applications of hyperpolarised magnetic resonance.

Journal article

Timm KN. et al, (2018), Prog Nucl Magn Reson Spectrosc, 106-107, 66 - 87

Hyperpolarized ketone body metabolism in the rat heart.

Journal article

Miller JJ. et al, (2018), NMR Biomed, 31

Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance.

Journal article

Lewis AJM. et al, (2018), Circ Res, 122, 1084 - 1093

Susceptibility-induced distortion correction in hyperpolarized echo planar imaging.

Journal article

Miller JJ. et al, (2018), Magn Reson Med, 79, 2135 - 2141

Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY.

Journal article

Guida C. et al, (2018), Diabetes Obes Metab, 20, 571 - 581

Protocols and Methodologies in Basic Science and Clinical Cardiac MRI

Book

(2018)

Prevalence and severity of non-alcoholic fatty liver disease are underestimated in clinical practice: impact of a dedicated screening approach at a large university teaching hospital.

Journal article

Marjot T. et al, (2018), Diabet Med, 35, 89 - 98

Weighted averaging in spectroscopic studies improves statistical power.

Journal article

Miller JJ. et al, (2017), Magn Reson Med, 78, 2082 - 2094

Myocyte metabolic imaging with hyperpolarised MRI

Chapter

Miller JJ., (2017), Protocols and Methodologies in Basic Science and Clinical Cardiac MRI, 111 - 173

The Role of PYY in Pancreatic Islet Physiology and Surgical Control of Diabetes.

Journal article

Guida C. et al, (2017), Trends Endocrinol Metab, 28, 626 - 636

HYPERPOLARIZED MAGNETIC RESONANCE IMAGING OF CARDIAC INFLAMMATION AND REPAIR

Conference paper

Lewis AJM. et al, (2017), HEART, 103, A151 - A151

The role of PYY in pancreatic islet physiology and surgical control of diabetes

Journal article

Guida C. et al, (2017), Trends in Endocrinology and Metabolism

Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1-13C]pyruvate.

Journal article

Lau AZ. et al, (2017), Magn Reson Med, 77, 1810 - 1817

Hyperpolarised MRI of cardiac inflammation and repair

Poster

Lewis A. et al, (2017), LANCET, 389, 62 - 62

On the Metabolism of Exogenous Ketones in Humans.

Journal article

Stubbs BJ. et al, (2017), Front Physiol, 8

Simultaneous assessment of cardiac metabolism and perfusion using copolarized [1-13 C]pyruvate and 13 C-urea.

Journal article

Lau AZ. et al, (2017), Magn Reson Med, 77, 151 - 158

Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS.

Journal article

Le Page LM. et al, (2016), NMR Biomed, 29, 1759 - 1767

Assessment of Metformin-Induced Changes in Cardiac and Hepatic Redox State Using Hyperpolarized[1-13C]Pyruvate.

Journal article

Lewis AJM. et al, (2016), Diabetes, 65, 3544 - 3551

GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.

Journal article

Veprik A. et al, (2016), FASEB J, 30, 3860 - 3869

NON-INVASIVE ASSESSMENT OF METFORMIN INDUCED CHANGES IN CARDIAC AND HEPATIC REDOX STATE USING HYPERPOLARIZED [1-13C] PYRUVATE

Conference paper

Lewis AJM. et al, (2016), HEART, 102, A14 - A14

Fast Padé Transform Accelerated CSI for Hyperpolarized MRS.

Journal article

Hansen ESS. et al, (2016), Tomography, 2, 117 - 124

Robust and high resolution hyperpolarized metabolic imaging of the rat heart at 7 T with 3D spectral-spatial EPI.

Journal article

Miller JJ. et al, (2016), Magn Reson Med, 75, 1515 - 1524

Cardiac perfusion imaging using hyperpolarized (13)C urea using flow sensitizing gradients.

Journal article

Lau AZ. et al, (2016), Magn Reson Med, 75, 1474 - 1483

Imaging Bone-Cartilage Interactions in Osteoarthritis Using [18F]-NaF PET-MRI.

Journal article

Savic D. et al, (2016), Mol Imaging, 15, 1 - 12

Modeling predicts a connection between sinus vortex effects and aortic compliance

Journal article

Aboelkassem Y. et al, (2016), Journal of Theoretical Biology, 389, 306 - 309

Cartilage T 1ρ and T 2 relaxation times: longitudinal reproducibility and variations using different coils, MR systems and sites

Journal article

Li X. et al, (2015), Osteoarthritis and Cartilage, 23, 2214 - 2223

In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy.

Journal article

Seymour A-ML. et al, (2015), Cardiovasc Res, 106, 249 - 260

Correction.

Journal article

(2015), Proc Natl Acad Sci U S A, 112

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function.

Journal article

Lakhal-Littleton S. et al, (2015), Proc Natl Acad Sci U S A, 112, 3164 - 3169

Mathematical modeling of aortic valve dynamics during systole

Journal article

Aboelkassem Y. et al, (2015), Journal of Theoretical Biology, 365, 280 - 288

Assessing Biological Response to Bevacizumab Using 18F-Fluoromisonidazole PET/MR Imaging in a Patient with Recurrent Anaplastic Astrocytoma

Journal article

Barajas RF. et al, (2015), Case Reports in Radiology, 2015, 1 - 4

The effect of magnetic field on positron range and spatial resolution in an integrated whole-body time-of-flight PET/MRI system

Journal article

Shih-ying Huang None. et al, (2014), 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

Mechanisms of cell migration in the adult brain: modelling subventricular neurogenesis.

Journal article

Van Schepdael A. et al, (2013), Comput Methods Biomech Biomed Engin, 16, 1096 - 1105

The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention.

Journal article

Sharoni Y. et al, (2012), Am J Clin Nutr, 96, 1173S - 1178S

A mathematical model of adult subventricular neurogenesis.

Journal article

Ashbourn JMA. et al, (2012), J R Soc Interface, 9, 2414 - 2423

Polyphenols, isothiocyanates, and carotenoid derivatives enhance estrogenic activity in bone cells but inhibit it in breast cancer cells.

Journal article

Veprik A. et al, (2012), Am J Physiol Endocrinol Metab, 303, E815 - E824

GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 and GPR41 proteins.

Journal article

Bahar Halpern K. et al, (2012), J Biol Chem, 287, 20154 - 20163

Carotenoids and apocarotenoids in cellular signaling related to cancer: a review.

Journal article

Sharoni Y. et al, (2012), Mol Nutr Food Res, 56, 259 - 269

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Fellows' Publications

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