We are a large multi-disciplinary department, which aims to tackle some of the world’s biggest health challenges by integrating innovative basic biology with cutting edge clinical research. We have internationally renowned programmes in a range of areas including cardiovascular sciences, diabetes and endocrinology, immunology, haematology and pathology.
Phenotypic and molecular characterization of a serum-free miniature erythroid differentiation system suitable for high-throughput screening and single-cell assays.
Mettananda S. et al, (2018), Exp Hematol, 60, 10 - 20
Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis-regulatory interactions and gene expression in the chicken embryo.
Williams RM. et al, (2018), Development, 145
MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Howson LJ. et al, (2018), Nat Commun, 9
In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.
Wu Q. et al, (2017), Nat Commun, 8
Karamitros D. et al, (2018), Nat Immunol, 19, 85 - 97