Nuffield Division of Clinical Laboratory Sciences
Head of Division
About NDCLS
Our aim is to study the pathology of human disease from the molecular to systems level, and to translate our findings into treatments for human disorders.
Read moreLatest Publications
Phenotypic and molecular characterization of a serum-free miniature erythroid differentiation system suitable for high-throughput screening and single-cell assays.
Mettananda S. et al, (2018), Exp Hematol, 60, 10 - 20
Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis-regulatory interactions and gene expression in the chicken embryo.
Williams RM. et al, (2018), Development, 145
Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.
Mettananda S. et al, (2017), Nat Commun, 8
Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response.
Amatangelo MD. et al, (2017), Blood, 130, 732 - 741
Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia.
Stein EM. et al, (2017), Blood, 130, 722 - 731
The Latest News
New funding for early diagnosis research using platelets
30 March 2021
Dr Bethan Psaila and her team will investigate the potential of circulating blood platelets for early detection of a range of cancer types.
TP53 gene determines severe blood cancer development
13 August 2020
New RDM Associate Professors and University Research Lecturers
10 July 2020
Many congratulations to our researchers.