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Contact information
Research groups
Colleges
Yi-Ling Chen
DPhil in Medical Sciences
Senior Postdoctoral Scientist
Research Summary
I joined the lab of Professor Graham Ogg as a DPhil student in 2014 to investigate the immune networks in human cutaneous inflammation and the translational development of novel therapeutic approaches. My work has been focusing on understanding the interaction and modulation of key innate immune cells in inflammatory conditions, and to identify novel therapeutic targets in sterile skin inflammation and cutaneous and systemic bacterial infection. Since completing my DPhil, I have continued my research as a Postdoctoral researcher, expanding my expertise and investigating the role of unconventional T cells in skin infectious and inflammatory diseases, adopting high-dimensional approaches and T cell cloning techniques
Recent publications
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Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.
Journal article
Monnot GC. et al, (2022), Nat Immunol
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CD1a promotes systemic manifestations of skin inflammation.
Journal article
Hardman CS. et al, (2022), Nat Commun, 13
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Dengue virus co-opts innate type 2 pathways to escape early control of viral replication.
Journal article
Fonseka CL. et al, (2022), Commun Biol, 5
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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
Journal article
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58
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Phospholipase activity of acyloxyacyl hydrolase induces IL-22-producing CD1a-autoreactive T cells in individuals with psoriasis.
Journal article
Singh R. et al, (2022), Eur J Immunol, 52, 511 - 524