UKPDS Legacy Study
UKPDS was a randomised, multicentre trial of glucose-lowering and antihypertensive therapies in patients with newly diagnosed type 2 diabetes. The study showed that complications of diabetes could be reduced by more intensive blood glucose and/or blood pressure control using existing treatments and dramatically changed the management of type 2 diabetes worldwide.
The UKPDS Legacy Study is an extended follow-up of UKPDS using electronic health records and other routinely collected health data.
The UKPDS Legacy Study intends to obtain updated forty-year follow-up data for the original participants of the UKPDS study by accessing electronic health record data via NHS Digital and NHS Scotland.
To investigate whether early more intensive blood glucose and/or blood pressure control is associated with:
- A reduction in the risk of dementia
- A reduced risk of major vascular disease in the longer term
To assess the health economic impact of early more intensive blood glucose and/or blood pressure control over a lifetime horizon
If you were a UKPDS participant, you can read the privacy notice for the UKPDS Legacy study here.