Publications — Radcliffe Department of Medicine

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TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.

Eyres M. et al, (2021), Gastroenterology, 161, 653 - 668.e16

Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments.

Kanellakis NI. et al, (2020), Thorax, 75, 1004 - 1008

The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells.

Hu Z. et al, (2020), Cancer Cell, 37, 226 - 242.e7

A Comprehensive Analysis of Key Immune Checkpoint Receptors on Tumor-Infiltrating T Cells From Multiple Types of Cancer.

Li X. et al, (2019), Front Oncol, 9

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis

Alton EWFW. et al, (2016)

Preparation for a First-in-Man Lentivirus Trial in Cystic Fibrosis Patients

Griesenbach U. et al, (2016), MOLECULAR THERAPY, 24, S214 - S214

A Phase 2b clinical trial of non-viral gene therapy in Cystic Fibrosis patients: randomized, double-blind, placebo-controlled repeated aerosol delivery to the lungs.

Gill DR. et al, (2015), HUMAN GENE THERAPY, 26, A18 - A18

Clinical Development of an Optimal F/HN Pseudotyped SIV Vector for Cystic Fibrosis Lung Gene Therapy

Pringle IA. et al, (2014), MOLECULAR THERAPY, 22, S141 - S141

MOVING TOWARD ASSESSMENT OF LENTIVIRAL VECTOR IN CLINICAL TRIAL

Griesenbach U. et al, (2014), PEDIATRIC PULMONOLOGY, 49, 297 - 297

MULTIPLE DOSES OF LIPID-MEDIATED GENE THERAPY NEBULISED TO THE MOUSE LUNG SHOW ROBUST AND SUSTAINED CFTR EXPRESSION

Hyde SC. et al, (2011), PEDIATRIC PULMONOLOGY, 281 - 281

Gene therapy for cystic fibrosis lung disease

Sumner-Jones SG. et al, (2010), 47 - 64

Optimising Harvest of Bronchial Brush Biopsy Samples To Maximise Cell and RNA Yield in Gene Therapy Studies

Vrettou C. et al, (2009), MOLECULAR THERAPY, 17, S125 - S125

Assessment of CFTR function after gene transfer in vitro and in vivo.

Griesenbach U. et al, (2008), Methods Mol Biol, 433, 229 - 242

Direct electroporation of the murine lung greatly enhances reporter gene expression following intranasal delivery of plasmid DNA

Pringle IA. et al, (2004), JOURNAL OF GENE MEDICINE, 6, S18 - S18

Use of ciliated cell specific promoter FoxJ1 in gene transfer vectors for the airway epithelium

Lawton AE. et al, (2004), MOLECULAR THERAPY, 9, S55 - S55

Include forthcoming?