Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Cross-presentation is important for regulating T-cell responses to exogenous antigens and can maintain tolerance (cross-tolerance) or induce immune responses (cross-priming). Recent exciting results on the role of the Toll-like receptor TLR3 in promoting cross-priming of viral antigens provide new insights into the mechanisms that allow Toll-like receptor signaling to bridge innate and adaptive immune responses.

Original publication

DOI

10.1016/j.cub.2005.04.025

Type

Journal article

Journal

Curr Biol

Publication Date

10/05/2005

Volume

15

Pages

R336 - R339

Keywords

Antigen Presentation, Antigens, Viral, Cross-Priming, Dendritic Cells, Humans, Immunity, Cellular, Membrane Glycoproteins, RNA, Double-Stranded, Receptors, Cell Surface, Signal Transduction, T-Lymphocytes, Toll-Like Receptor 3, Toll-Like Receptors