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The aim of our study was to evaluate the Greek version of the transfusion-dependent quality of life (TranQol) questionnaire and report our experience of using this novel disease-specific quality of life (QoL) measure in patients with transfusion-dependent thalassemia (TDT). The TranQol and SF-36v2 questionnaires were administered to 94 adult TDT patients with a mean age of 32.1 years (SD = 7, range = 19-58), recruited from the Adult Thalassemia Unit of Hippokration General Hospital of Thessaloniki, Greece. The TranQol was evaluated in terms of construct validity, reliability, and responsiveness. There was a moderately strong correlation between the TranQol summary and both the SF-36v2 physical and mental component summaries (r = 0.4, p 

Original publication




Journal article


Ann Hematol

Publication Date





1937 - 1944


Beta-thalassemia major, Patient-reported outcome measures, Quality of life, Transfusion-dependent thalassemia, Adult, Blood Transfusion, Cross-Sectional Studies, Female, Greece, Humans, Iron Chelating Agents, Longitudinal Studies, Male, Middle Aged, Quality of Life, Reproducibility of Results, Surveys and Questionnaires, beta-Thalassemia