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Appropriate control of blood pressure (BP) in hypertensive patients still represents the major therapeutic goal in the treatment of hypertension. Despite the growing attention and wide range of antihypertensive agents available in the clinical scenario, the target of BP below the advised thresholds of 140/90 mmHg is, unfortunately, often unreached. For this reason, the search for new antihypertensive agents is still ongoing. Azilsartan medoxomil, a new angiotensin receptor blocker that has been recently introduced in the clinical arena, represents the eighth angiotensin receptor blocker currently available for BP control. The aim of this paper is to describe the efficacy and safety profile of this new compound, reviewing available data obtained from both pre-clinical and clinical studies.

Original publication

DOI

10.2147/VHRM.S22589

Type

Journal article

Journal

Vasc Health Risk Manag

Publication Date

2012

Volume

8

Pages

299 - 305

Keywords

angiotensin receptor blocker, azilsartan medoxomil, hypertension, Angiotensin II Type 1 Receptor Blockers, Animals, Antihypertensive Agents, Benzimidazoles, Blood Pressure, Drug Interactions, Evidence-Based Medicine, Humans, Hypertension, Oxadiazoles, Renin-Angiotensin System, Risk Assessment, Treatment Outcome