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AIMS: The age-thrombus burden-index of microcirculatory resistance (ATI) score is a diagnostic tool able to predict suboptimal myocardial reperfusion before stenting, in patients with ST-elevation myocardial infarction (STEMI). We aimed to validate the ATI score against cardiac magnetic resonance imaging (cMRI). METHODS AND RESULTS: The ATI score was calculated prospectively in 80 STEMI patients. cMRI was performed within 48 hours in all patients and in 50 patients at six-month follow-up to assess the extent of infarct size (IS%) and microvascular obstruction (MVO%). The ATI score was calculated using age (>50=1 point), pre-stenting index of microcirculatory resistance (IMR) (>40 and <100=1 point; ≥100=2 points) and angiographic thrombus score (4=1 point; 5=3 points). ATI score was closely related to final IS% (ATI.

Original publication




Journal article



Publication Date





935 - 943


Aged, Aged, 80 and over, Coronary Circulation, Female, Humans, Magnetic Resonance Imaging, Male, Microcirculation, Middle Aged, Myocardial Infarction, Myocardial Reperfusion, Percutaneous Coronary Intervention, ST Elevation Myocardial Infarction, Treatment Outcome