Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

There are a number of autoimmune subepidermal blistering disorders in which the presence of autoantibodies has been well documented. These include pemphigoid gestationis, linear immunoglobulin A disease, bullous pemphigoid, lichen planus pemphigoides and mucous membrane pemphigoid. The antibodies involved in these diseases are commonly directed against protein components of the basement membrane zone. The requirement for T cells in the production of autoantibodies, the infiltration of T cells into lesions and HLA-associations have led to a number of investigations into the role of T cells in these diseases. This review will concentrate on the evidence for the role of T cells in the pathogenesis of mucous membrane pemphigoid. © 2006, Future Drugs Ltd. All rights reserved.

Original publication




Journal article


Expert Review of Dermatology

Publication Date





25 - 30