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INTRODUCTION: Increased blood pressure (BP) variability is a cardiovascular risk marker for young individuals and may relate to the ability of their aorta to buffer cardiac output. We used a multimodality approach to determine relations between central and peripheral arterial stiffness and BP variability. METHODS: We studied 152 adults (mean age of 31 years) who had BP variability measures based on SD of awake ambulatory BPs, 24-h weighted SD and average real variability (ARV). Global and regional aortic distensibility was measured by cardiovascular magnetic resonance, arterial stiffness by cardio-ankle vascular index (CAVI) and pulse wave velocity (PWV) by SphygmoCor (carotid-femoral) and Vicorder (brachial-femoral). RESULTS: In young people, free from overt cardiovascular disease, all indices of SBP and DBP variability correlated with aortic distensibility (global aortic distensibility versus awake SBP SD: r = -0.39, P 

Original publication




Journal article


J Hypertens

Publication Date





513 - 522


Adult, Aorta, Blood Pressure, Blood Pressure Monitoring, Ambulatory, Cardiovascular Diseases, Carotid Arteries, Female, Femoral Artery, Humans, Hypertension, Magnetic Resonance Imaging, Male, Middle Aged, Pulse Wave Analysis, Risk Factors, Vascular Stiffness, Young Adult