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Reduction of active disease by preventive therapy has the potential to make an important contribution towards the goal of tuberculosis (TB) elimination. This report summarises discussions amongst a Working Group convened to consider areas of research that will be important in optimising the design and delivery of preventative therapies. The Working Group met in Cape Town on 26th February 2012, following presentation of results from the GC11 Grand Challenges in Global Health project to discover drugs for latent TB.

Original publication

DOI

10.1016/j.tube.2012.06.004

Type

Journal article

Journal

Tuberculosis (Edinb)

Publication Date

11/2012

Volume

92

Pages

447 - 452

Keywords

Antitubercular Agents, Bacterial Load, Biomarkers, Drug Design, Female, Humans, Immunization Programs, Latent Tuberculosis, Male, Models, Animal, Mycobacterium tuberculosis, South Africa, Tuberculosis, Tuberculosis Vaccines