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The International Pancreas and Islet Transplant Association (IPITA), in conjunction with the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.

Original publication

DOI

10.1097/TP.0000000000001054

Type

Journal article

Journal

Transplantation

Publication Date

07/2016

Volume

100

Pages

e25 - e31

Keywords

Animals, Cell Proliferation, Congresses as Topic, Diabetes Mellitus, Type 1, Humans, Immune Tolerance, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Islets of Langerhans Transplantation, Pancreas, Pancreas Transplantation, Regeneration, Societies, Medical, Swine, Transplantation, Heterologous, Transplantation, Homologous, United States