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The inherited disorders of hemoglobin, the most common monogenic diseases, are now well understood at the molecular and cellular level, knowledge which has led to considerable Improvements in their control and management. Because of their particularly high gene frequencies in sub-Saharan Africa, the Indian subcontinent, and throughout Southeast Asia, the organization of their control and treatment provides a major challenge for the new millennium.


Journal article


Semin Hematol

Publication Date





24 - 37