The Collaborative Cross, a community resource for the genetic analysis of complex traits.
Churchill GA., Airey DC., Allayee H., Angel JM., Attie AD., Beatty J., Beavis WD., Belknap JK., Bennett B., Berrettini W., Bleich A., Bogue M., Broman KW., Buck KJ., Buckler E., Burmeister M., Chesler EJ., Cheverud JM., Clapcote S., Cook MN., Cox RD., Crabbe JC., Crusio WE., Darvasi A., Deschepper CF., Doerge RW., Farber CR., Forejt J., Gaile D., Garlow SJ., Geiger H., Gershenfeld H., Gordon T., Gu J., Gu W., de Haan G., Hayes NL., Heller C., Himmelbauer H., Hitzemann R., Hunter K., Hsu H-C., Iraqi FA., Ivandic B., Jacob HJ., Jansen RC., Jepsen KJ., Johnson DK., Johnson TE., Kempermann G., Kendziorski C., Kotb M., Kooy RF., Llamas B., Lammert F., Lassalle J-M., Lowenstein PR., Lu L., Lusis A., Manly KF., Marcucio R., Matthews D., Medrano JF., Miller DR., Mittleman G., Mock BA., Mogil JS., Montagutelli X., Morahan G., Morris DG., Mott R., Nadeau JH., Nagase H., Nowakowski RS., O'Hara BF., Osadchuk AV., Page GP., Paigen B., Paigen K., Palmer AA., Pan H-J., Peltonen-Palotie L., Peirce J., Pomp D., Pravenec M., Prows DR., Qi Z., Reeves RH., Roder J., Rosen GD., Schadt EE., Schalkwyk LC., Seltzer Z., Shimomura K., Shou S., Sillanpää MJ., Siracusa LD., Snoeck H-W., Spearow JL., Svenson K., Tarantino LM., Threadgill D., Toth LA., Valdar W., de Villena FP-M., Warden C., Whatley S., Williams RW., Wiltshire T., Yi N., Zhang D., Zhang M., Zou F., Complex Trait Consortium None.
The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.