Clinical studies with vasodilators in heart failure
Ertl G., Gaudron P., Neubauer S.
The value of vasodilator therapy in acute and chronic heart failure is well established. Vasodilators improve symptoms and prognosis in patients with severe clinical symptoms refractory to the treatment with diuretics and digitalis. Angiotensin-converting enzyme (ACE) inhibitors were beneficial even in less severe heart failure. Most recent studies suggest that prevention of heart failure is possible in patients with severe left ventricular dysfunction.