Structure of the granulocyte macrophage colony-stimulating factor gene in patients with the myelodysplastic syndromes.
Boultwood J., Abrahamson G., Buckle VJ., Rack K., Oscier DG., Wainscoat JS.
DNA samples from 76 patients with the myelodysplastic syndromes, including 10 cases with a partial deletion of the long arm of chromosome 5 (5q-), were examined for structural rearrangements of the granulocyte/macrophage colony-stimulating factor (GM-CSF) gene. No abnormalities were detected, indicating that structural aberrations of this gene are not a feature of the myelodysplastic syndromes.