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DNA samples from 76 patients with the myelodysplastic syndromes, including 10 cases with a partial deletion of the long arm of chromosome 5 (5q-), were examined for structural rearrangements of the granulocyte/macrophage colony-stimulating factor (GM-CSF) gene. No abnormalities were detected, indicating that structural aberrations of this gene are not a feature of the myelodysplastic syndromes.

Type

Journal article

Journal

Am J Hematol

Publication Date

06/1990

Volume

34

Pages

157 - 158

Keywords

Colony-Stimulating Factors, Gene Amplification, Genes, Granulocyte-Macrophage Colony-Stimulating Factor, Growth Substances, Humans, Myelodysplastic Syndromes