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Recent studies have identified new melanoma antigens that are recognised by CD4(+) T cells. Analysis of tumour-specific CD4(+) T-cell responses may lead to the development of optimal anti-cancer vaccines that can induce an orchestrated effort of tumour-specific CD4(+) and CD8(+) T cells in the fight against cancer.

Type

Journal article

Journal

Curr Biol

Publication Date

23/09/1999

Volume

9

Pages

R695 - R697

Keywords

Animals, Antigen Presentation, Antigens, Neoplasm, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cancer Vaccines, Histocompatibility Antigens Class II, Immunologic Surveillance, Melanoma, Mice, Models, Immunological, Neoplasms, Neoplasms, Experimental