Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Spontaneously beating atrial preparations, from rats fed different lipid diets, were compressed to 10 MPa. The following observations were made: Different lipid diets altered the ratio of omega-6/omega-3 polyunsaturated fatty acids of the cardiac phospholipids. Beating frequency and twitch tension at surface pressure was unaffected by the diets. Compression to 10 MPa caused a decrease in spontaneous beating frequency and an increased twitch tension in all preparations. The decrease in beating frequency was inversely related to the omega-6/omega-3 ratio. Pressure induced increase in twitch tension was not affected by the diets. N2O dissolved in the tissue bath solution partly counteracted the pressure-induced changes.

Type

Journal article

Journal

Undersea Biomed Res

Publication Date

01/1987

Volume

14

Pages

31 - 43

Keywords

Animals, Dietary Fats, Female, Heart Atria, Heart Rate, Hydrostatic Pressure, Isometric Contraction, Membrane Lipids, Myocardial Contraction, Myocardium, Phospholipids, Pressure, Rats, Rats, Inbred Strains, Respiration