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Recent studies have highlighted the role of inflammatory mediators and the cells of the innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic plaques. Viewing this form of vascular pathology as a modified form of chronic inflammation suggests new avenues for therapeutic intervention in cardiovascular disease.


Journal article


Trends Immunol

Publication Date





535 - 541


Animals, Anti-Inflammatory Agents, Arteriosclerosis, Cardiovascular Diseases, Cell Movement, Humans, Inflammation, Inflammation Mediators, Leukocytes, Models, Immunological