Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

In order to study the impact of high-density lipoproteins (HDL) subclasses on the ability of HDL to act as substrate for lecithin: cholesterol acyltransferase (LCAT), we isolated HDL from nine normolipidemic male subjects. The HDL particle size distribution was analysed by gradient gel electrophoresis and the esterification rate of the isolated homologous HDL was compared with a pool of HDL where all the nine subjects took part. It was found that the strongest determinant for HDL cholesterol esterification rate was the inhibitory action of HDL subclass 2B.


Journal article


Biochim Biophys Acta

Publication Date





310 - 314


Adult, Cholesterol Esters, Cholesterol, HDL, Dietary Fats, Electrophoresis, Polyacrylamide Gel, Fasting, Humans, Lipids, Lipoproteins, HDL, Male, Phosphatidylcholine-Sterol O-Acyltransferase, Substrate Specificity