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Life-threatening iron overload may occur without severe anaemia in patients with sideroblastic disorders. Assessment of erythroid expansion in bone-marrow aspirates may be as useful as ferrokinetic studies in predicting both the risk of iron loading and the need for prophylactic phlebotomy or iron-chelation therapy.

Type

Journal article

Journal

Lancet

Publication Date

19/02/1983

Volume

1

Pages

375 - 378

Keywords

Adult, Anemia, Sideroblastic, Bloodletting, Chelating Agents, Diet, Erythrocyte Indices, Female, HLA Antigens, Humans, Intestinal Absorption, Iron, Male, Middle Aged, Risk