Red cell transfusion thresholds in outpatients with myelodysplastic syndromes: Results of a pilot randomized trial RBC-ENHANCE.
Buckstein R., Callum J., Prica A., Bowen D., Wells RA., Leber B., Heddle N., Chodirker L., Cheung M., Mozessohn L., Yee K., Gallagher J., Parmentier A., Jamula E., Zhang L., Mamedov A., Stanworth SJ., Lin Y.
BACKGROUND: The optimal hemoglobin (Hb) threshold for red blood cell transfusions in adult patients with myelodysplastic syndromes (MDS) has not been defined. STUDY DESIGN AND METHODS: We conducted a pilot randomized multi-center study of two transfusion algorithms (liberal, to maintain Hb 110-120 g/L, transfuse 2 units if Hb