Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Magnetic resonance spectroscopy (MRS) is a versatile and powerful tool for the non invasive study of cardiac metabolism and can be used to measure myocardial concentrations of many different metabolites. The most widely studied nucleus, phosphorus-31, allows for the detection of phosphocreatine, ATP, intracellular pH, and flux through the creatine kinase reaction. Carbon-13-MRS has a low sensitivity, but several metabolites can be measured to facilitate study of substrate utilization and flux. Finally, hydrogen-1 (proton)-MRS can be used to study myocardial oxygenation and creatine concentrations. Here, we give a brief overview of the different applications of cardiac MRS and the pathophysiological insights derived from such studies.

Type

Journal article

Journal

Heart and Metabolism

Publication Date

10/11/2006

Pages

18 - 21