Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Hormones are dynamically collected by fenestrated capillaries to generate pulses, which are then decoded by target tissues to mount a biological response. To generate hormone pulses, endocrine systems have evolved mechanisms to tightly regulate blood perfusion and oxygenation, coordinate endocrine cell responses to secretory stimuli, and regulate hormone uptake from the perivascular space into the bloodstream. Based on recent findings, we review here the mechanisms that exist in endocrine systems to regulate blood flow, and facilitate coordinated cell activity and output under both normal physiological and pathological conditions in the pituitary gland and pancreas.

Original publication

DOI

10.1530/JME-11-0035

Type

Journal article

Journal

J Mol Endocrinol

Publication Date

2011

Volume

47

Pages

R59 - R66

Keywords

Animals Endocrine Cells/*metabolism Endocrine System/*blood supply/cytology/*metabolism Humans Pancreas/blood supply/cytology/metabolism Pituitary Gland/blood supply/cytology/metabolism