Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

A detailed sequence comparison of the MSX homeobox family sheds light on its evolution and identifies new conserved motifs. But in the absence of corroborative genetic data, phylogenomics alone can provide only limited insights into the pathogenicity of heterozygous missense substitutions in human genes.

Original publication

DOI

10.1186/jbiol127

Type

Journal article

Journal

J Biol

Publication Date

2009

Volume

8

Keywords

Amino Acid Sequence, Base Sequence, Conserved Sequence, Genetic Predisposition to Disease, Genomics, Homeodomain Proteins, Humans, MSX1 Transcription Factor, Mouth Abnormalities, Mutation