Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Precise counting of platelets is difficult particularly in the low thrombocytopenic range or when large platelets exist. The recently available Bayer ADVIA 120 analyser uses a method of counting platelets based on two dimensional laser light scatter. We have evaluated this technique on an analysis of 217 peripheral blood samples and found significant differences in platelet counts compared with values obtained by impedance technology, when the causes of thrombocytopenia were due to peripheral platelet consumption. Moreover, such differences were more marked in those samples from severely thrombocytopenic individuals with large platelets on the blood film. These differences, which warrant further study, may have significant implications for the management of patients with very low platelet counts.

Original publication

DOI

10.1046/j.1365-2257.1999.00200.x

Type

Journal article

Journal

Clin Lab Haematol

Publication Date

04/1999

Volume

21

Pages

113 - 117

Keywords

Blood Platelets, Humans, Platelet Count, Thrombocytopenia