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We report the case of a 46-year-old male who developed dermatomyositis and a sarcoid-like reaction in association with testicular relapse of multiple myeloma. The myositis progressed despite chemotherapy directed at the underlying malignant disorder and immunosuppressive treatment. There was, however, a dramatic and sustained response to high-dose chemotherapy and autologous peripheral blood stem cell transplantation which resulted in resolution of the myopathy and partial resolution of the sarcoid-like reaction. This case report highlights the potential of autologous stem cell transplantation as treatment for para-neoplastic disorders associated with haematological malignancies.

Original publication

DOI

10.1038/sj.bmt.1703048

Type

Journal article

Journal

Bone Marrow Transplant

Publication Date

06/2001

Volume

27

Pages

1215 - 1217

Keywords

Antineoplastic Combined Chemotherapy Protocols, Combined Modality Therapy, Dermatomyositis, Hematopoietic Stem Cell Transplantation, Humans, Male, Middle Aged, Multiple Myeloma, Recurrence, Sarcoidosis, Testicular Neoplasms, Treatment Outcome