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A young adult with homozygous sickle cell anaemia (Hb SS) suffered a fatal sickle cell crisis complicated by the sickle chest syndrome. At necropsy multiple large infarcts of the lung, bone marrow, and pituitary gland were found. The large majority of pulmonary infarcts were not associated with either gross or microscopic vaso-occlusion. These findings are discussed and correlated with past and current opinions of sickle cell crisis and the sickle chest syndrome.

Type

Journal article

Journal

J Clin Pathol

Publication Date

06/1985

Volume

38

Pages

659 - 664

Keywords

Adult, Anemia, Sickle Cell, Female, Humans, Infarction, Vascular Diseases