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Contact information
Surawee Chuaiphichai
BSc (Hons), DPhil
Postdoctoral Research Scientist
I am a postdoctoral research fellow in Prof Keith Channon's laboratory in the Division of Cardiovascular Medicine. I completed my DPhil in 2014 in which I studied the role of endothelial cell Gch1 and tetrahydrobiopterin (BH4) biosynthesis in vascular function and blood pressure regulation. I am currently investigating the role of endothelial cell BH4-dependent NOS regulation in vascular adaptations and blood pressure regulation in normal pregnancy using a novel mouse model of endothelial cell BH4 deficiency (endothelial cell-targeted Gch1 knockout mouse).
Recent publications
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Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice.
Journal article
Chuaiphichai S. et al, (2023), Vascul Pharmacol, 150
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Endothelial Cell-Specific Roles for Tetrahydrobiopterin in Myocardial Function, Cardiac Hypertrophy and Response to Myocardial Ischemia-Reperfusion Injury.
Journal article
Chuaiphichai S. et al, (2023), Am J Physiol Heart Circ Physiol
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Effects of canagliflozin on human myocardial redox signalling: clinical implications.
Journal article
Kondo H. et al, (2021), Eur Heart J, 42, 4947 - 4960
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Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth.
Journal article
Chuaiphichai S. et al, (2021), Hypertension
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Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With Cardiovascular Disease.
Journal article
Akawi N. et al, (2021), J Am Coll Cardiol, 77, 2494 - 2513