Publications — Radcliffe Department of Medicine

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Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition.

Akoumianakis I. et al, (2020), Sci Transl Med, 12

Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.

Patel J. et al, (2018), Vascul Pharmacol, 108, 15 - 22

Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.

Douglas G. et al, (2018), Cardiovasc Res, 114, 1385 - 1399

Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm.

Chuaiphichai S. et al, (2018), Hypertension, 72, 128 - 138

Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II–mediated blood pressure control

Patel J. et al, (2018), Vascular Pharmacology

A new role for RGS-1 in vascular function and blood pressure regulation

Patel J. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S88 - S88

Deficiency in endothelial cell tetrahydrobiopterin increases resistance vascular remodelling, blood pressure, and susceptibility to aortic abdominal aneurysm in response to angiotensin II

Chuaiphichai S. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S90 - S90

A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.

Chuaiphichai S. et al, (2017), Br J Pharmacol, 174, 657 - 671

Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension.

Chuaiphichai S. et al, (2016), Vascul Pharmacol, 77, 69 - 79

The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.

Latremoliere A. et al, (2015), Neuron, 86, 1393 - 1406

Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.

McNeill E. et al, (2015), Free Radic Biol Med, 79, 206 - 216

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.

Chuaiphichai S. et al, (2014), Hypertension, 64, 530 - 540

NOS/redox-independent protective effects of GTP cyclohydrolase 1 (GCH1) overexpression and tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

Hijazo RC. et al, (2014), EUROPEAN HEART JOURNAL, 35, 1185 - 1186

303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.

Chuaiphichai S. et al, (2014), Cardiovasc Res, 103 Suppl 1

P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.

Duglan D. et al, (2014), Cardiovasc Res, 103 Suppl 1

201 Regulation of INOS Function, Redox State and NRF2 Activation by Macrophage GCH1 and Tetrahydrobiopterin.

McNeill E. et al, (2014), Heart, 100 Suppl 3, A110 - A111

Crucial role for neuronal nitric oxide synthase in early microcirculatory derangement and recipient survival following murine pancreas transplantation.

Cardini B. et al, (2014), PLoS One, 9

A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.

Benson MA. et al, (2013), J Biol Chem, 288, 29836 - 29845

Conditional knockout of GCH1 in leukocytes and endothelial cells: A novel model to study tetrahydrobiopterin-dependent NOS functions in vivo

McNeill E. et al, (2012), NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 27, S41 - S41

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