Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition.
Journal article
Akoumianakis I. et al, (2020), Sci Transl Med, 12
Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Journal article
Patel J. et al, (2018), Vascul Pharmacol, 108, 15 - 22
Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Journal article
Douglas G. et al, (2018), Cardiovasc Res, 114, 1385 - 1399
Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm.
Journal article
Chuaiphichai S. et al, (2018), Hypertension, 72, 128 - 138
Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II–mediated blood pressure control
Journal article
Patel J. et al, (2018), Vascular Pharmacology
A new role for RGS-1 in vascular function and blood pressure regulation
Conference paper
Patel J. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S88 - S88
Deficiency in endothelial cell tetrahydrobiopterin increases resistance vascular remodelling, blood pressure, and susceptibility to aortic abdominal aneurysm in response to angiotensin II
Conference paper
Chuaiphichai S. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S90 - S90
A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
Journal article
Chuaiphichai S. et al, (2017), Br J Pharmacol, 174, 657 - 671
Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension.
Journal article
Chuaiphichai S. et al, (2016), Vascul Pharmacol, 77, 69 - 79
The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy
Conference paper
Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775
Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Journal article
Latremoliere A. et al, (2015), Neuron, 86, 1393 - 1406
Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.
Journal article
McNeill E. et al, (2015), Free Radic Biol Med, 79, 206 - 216
Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Journal article
Chuaiphichai S. et al, (2014), Hypertension, 64, 530 - 540
NOS/redox-independent protective effects of GTP cyclohydrolase 1 (GCH1) overexpression and tetrahydrobiopterin (BH4) in diabetic cardiomyopathy
Conference paper
Hijazo RC. et al, (2014), EUROPEAN HEART JOURNAL, 35, 1185 - 1186
303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Conference paper
Chuaiphichai S. et al, (2014), Cardiovasc Res, 103 Suppl 1
P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.
Conference paper
Duglan D. et al, (2014), Cardiovasc Res, 103 Suppl 1
201 Regulation of INOS Function, Redox State and NRF2 Activation by Macrophage GCH1 and Tetrahydrobiopterin.
Conference paper
McNeill E. et al, (2014), Heart, 100 Suppl 3, A110 - A111
Crucial role for neuronal nitric oxide synthase in early microcirculatory derangement and recipient survival following murine pancreas transplantation.
Journal article
Cardini B. et al, (2014), PLoS One, 9
A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.
Journal article
Benson MA. et al, (2013), J Biol Chem, 288, 29836 - 29845
Conditional knockout of GCH1 in leukocytes and endothelial cells: A novel model to study tetrahydrobiopterin-dependent NOS functions in vivo
Conference paper
McNeill E. et al, (2012), NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 27, S41 - S41