Ricardo Carnicer

• The Subcellular Localisation of Neuronal Nitric Oxide Synthase Determines the Downstream Effects of NO on Myocardial Function.

  Journal article

  Carnicer R. et al, (2017), Cardiovasc Res

• Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts.

  Journal article

  Roselló-Lletí E. et al, (2016), Sci Rep, 6

• Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.

  Journal article

  Reilly SN. et al, (2016), Sci Transl Med, 8

• Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance.

  Journal article

  Roselló-Lletí E. et al, (2016), Sci Rep, 6

• Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.

  Journal article

  Hashimoto T. et al, (2016), J Am Heart Assoc, 5

• The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

  Conference paper

  Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775

• Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial-fibrillation-induced electrical remodelling in man.

  Journal article

  Reilly S. et al, (2015), Lancet, 385 Suppl 1

• Adenoviral transduction of FRET-based biosensors for cAMP in primary adult mouse cardiomyocytes.

  Chapter

  Lomas O. et al, (2015), 1294, 103 - 115

• Increased atrial fibrillation susceptibility in mice with myocardial specific NOX2 overexpression is prevented by short term statin treatment

  Conference paper

  Recalde A. et al, (2014), EUROPEAN HEART JOURNAL, 35, 1118 - 1118

• Nitric oxide synthase regulation of cardiac excitation-contraction coupling in health and disease.

  Other

  Simon JN. et al, (2014), J Mol Cell Cardiol, 73, 80 - 91

• P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.

  Conference paper

  Duglan D. et al, (2014), Cardiovasc Res, 103 Suppl 1

• P106Loss of myocardial nNOS in human atrial fibrillation (AF) shortens action potential duration (APD) by increasing Ito: Implications for AF-induced electrical remodelling.

  Journal article

  Liu X. et al, (2014), Cardiovasc Res, 103 Suppl 1

• Nitric oxide synthase regulation of cardiac excitation-contraction coupling in health and disease

  Journal article

  Simon JN. et al, (2014), Journal of Molecular and Cellular Cardiology, 73, 80 - 91

• Regulation of endothelial nitric-oxide synthase (NOS) S-glutathionylation by neuronal NOS: evidence of a functional interaction between myocardial constitutive NOS isoforms.

  Journal article

  Idigo WO. et al, (2012), J Biol Chem, 287, 43665 - 43673

• Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation

  Journal article

  Carnicer R. et al, (2012), Circulation Research, 111, 718 - 727

• Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.

  Journal article

  Carnicer R. et al, (2012), Circ Res, 111, 718 - 727

• NO from neuronal NO synthase increases after beta-adrenergic stimulation but does not control mitochondrial respiration

  Conference paper

  Bergem S. et al, (2012), EUROPEAN HEART JOURNAL, 33, 878 - 878

• Cardiomyocyte GTP Cyclohydrolase 1 and Tetrahydrobiopterin Accelerate Myocardial Relaxation by Increasing NOS1 Activity and Phospholamban Phosphorylation

  Journal article

  Carnicer R. et al, (2012), Circulation Research, In press

• Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation

  Journal article

  Carnicer R. et al, (2011), EUROPEAN HEART JOURNAL, 32, 154 - 154

• Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production

  Journal article

  Carnicer R. et al, (2010), CIRCULATION, 122

• Hyperhomocysteinemia. Current overview and contribution of mice to research on the topic

  Journal article

  Nuño-Ayala M. et al, (2010), Clinica e Investigacion en Arteriosclerosis, 22, 200 - 219

• Nitric oxide-releasing agent, LA419, reduces atherogenesis in apolipoprotein E-deficient mice.

  Journal article

  Carnicer R. et al, (2009), Naunyn Schmiedebergs Arch Pharmacol, 379, 489 - 500

• Is depressed myocyte contractility an early event in the natural history of heart failure?

  Journal article

  Idigo W. et al, (2008), EUROPEAN HEART JOURNAL, 29, 108 - 108

• Genetic background in apolipoprotein A-I and cystathionine beta-synthase deficiency.

  Journal article

  Carnicer R. et al, (2008), Front Biosci, 13, 5155 - 5162

• Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice.

  Journal article

  Guillén N. et al, (2008), Atherosclerosis, 197, 72 - 83

• Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine beta-synthase and apolipoprotein A-I.

  Journal article

  Carnicer R. et al, (2008), Naunyn Schmiedebergs Arch Pharmacol, 377, 35 - 43

• Extra virgin olive oils increase hepatic fat accumulation and hepatic antioxidant protein levels in APOE-/- mice.

  Journal article

  Arbones-Mainar JM. et al, (2007), J Proteome Res, 6, 4041 - 4054

• Accelerated atherosclerosis in apolipoprotein E-deficient mice fed Western diets containing palm oil compared with extra virgin olive oils: a role for small, dense high-density lipoproteins.

  Journal article

  Arbonés-Mainar JM. et al, (2007), Atherosclerosis, 194, 372 - 382

• Genetically based hypertension generated through interaction of mild hypoalphalipoproteinemia and mild hyperhomocysteinemia.

  Journal article

  Carnicer R. et al, (2007), J Hypertens, 25, 1597 - 1607

• Olive oil preparation determines the atherosclerotic protection in apolipoprotein E knockout mice.

  Journal article

  Acín S. et al, (2007), J Nutr Biochem, 18, 418 - 424

• Microarray analysis of hepatic genes differentially expressed in the presence of the unsaponifiable fraction of olive oil in apolipoprotein E-deficient mice.

  Journal article

  Acín S. et al, (2007), Br J Nutr, 97, 628 - 638

• Folic acid supplementation delays atherosclerotic lesion development in apoE-deficient mice

  Journal article

  Carnicer R. et al, (2007), Clinica e Investigacion en Arteriosclerosis, 19, 109 - 110

• Folic acid supplementation delays atherosclerotic lesion development in apoE-deficient mice.

  Journal article

  Carnicer R. et al, (2007), Life Sci, 80, 638 - 643

• Selective effect of conjugated linoleic acid isomers on atherosclerotic lesion development in apolipoprotein E knockout mice.

  Journal article

  Arbonés-Mainar JM. et al, (2006), Atherosclerosis, 189, 318 - 327

• Cystathionine beta-synthase is essential for female reproductive function.

  Journal article

  Guzmán MA. et al, (2006), Hum Mol Genet, 15, 3168 - 3176

• Hydroxytyrosol administration enhances atherosclerotic lesion development in apo E deficient mice.

  Journal article

  Acín S. et al, (2006), J Biochem, 140, 383 - 391

• Trans-10, cis-12- and cis-9, trans-11-conjugated linoleic acid isomers selectively modify HDL-apolipoprotein composition in apolipoprotein E knockout mice.

  Journal article

  Arbonés-Mainar JM. et al, (2006), J Nutr, 136, 353 - 359

• Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models.

  Journal article

  Sarria AJ. et al, (2006), Front Biosci, 11, 955 - 967

• Dietary cholesterol suppresses the ability of olive oil to delay the development of atherosclerotic lesions in apolipoprotein E knockout mice.

  Journal article

  Acín S. et al, (2005), Atherosclerosis, 182, 17 - 28

• Immune-regulation of the apolipoprotein A-I/C-III/A-IV gene cluster in experimental inflammation.

  Journal article

  Navarro MA. et al, (2005), Cytokine, 31, 52 - 63

• Response of ApoA-IV in pigs to long-term increased dietary oil intake and to the degree of unsaturation of the fatty acids.

  Journal article

  Navarro MA. et al, (2004), Br J Nutr, 92, 763 - 769

• Cloning, characterization and comparative analysis of pig plasma apolipoprotein A-IV.

  Journal article

  Navarro MA. et al, (2004), Gene, 325, 157 - 164

Selected Publications

• Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.

  Journal article

  Hashimoto T. et al, (2016), J Am Heart Assoc, 5

• Nitric oxide synthase regulation of cardiac excitation-contraction coupling in health and disease.

  Other

  Simon JN. et al, (2014), J Mol Cell Cardiol, 73, 80 - 91

• Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation

  Journal article

  Carnicer R. et al, (2012), Circulation Research, 111, 718 - 727

Recent Publications

• The Subcellular Localisation of Neuronal Nitric Oxide Synthase Determines the Downstream Effects of NO on Myocardial Function.

  Journal article

  Carnicer R. et al, (2017), Cardiovasc Res

• Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts.

  Journal article

  Roselló-Lletí E. et al, (2016), Sci Rep, 6

• Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.

  Journal article

  Reilly SN. et al, (2016), Sci Transl Med, 8

• Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance.

  Journal article

  Roselló-Lletí E. et al, (2016), Sci Rep, 6

• Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.

  Journal article

  Hashimoto T. et al, (2016), J Am Heart Assoc, 5