Publications — Radcliffe Department of Medicine

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Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.

Edgar L. et al, (2021), Circulation

BH4 Increases nNOS Activity and Preserves Left Ventricular Function in Diabetes.

Carnicer R. et al, (2021), Circ Res, 128, 585 - 601

Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice.

Mighiu AS. et al, (2021), Cardiovasc Res

Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: A randomised trial of atorvastatin.

Jayaram R. et al, (2020), Cardiovasc Res

Improved cellular uptake of perfluorocarbon nanoparticles for in vivo murine cardiac 19F MRS/MRI and temporal tracking of progenitor cells.

Constantinides C. et al, (2019), Nanomedicine, 18, 391 - 401

BH4 SUPPLEMENTATION AS A NEW TREATMENT FOR DIABETIC CARDIOMYOPATHY

Carnicer R. et al, (2019), HEART, 105, A153 - A153

Correction: Fast, quantitative, murine cardiac 19F MRI/MRS of PFCE-labeled progenitor stem cells and macrophages at 9.4T.

Constantinides C. et al, (2019), PLoS One, 14

In Vivo Tracking and 1H/19F Magnetic Resonance Imaging of Biodegradable Polyhydroxyalkanoate/Polycaprolactone Blend Scaffolds Seeded with Labeled Cardiac Stem Cells.

Constantinides C. et al, (2018), ACS Appl Mater Interfaces, 10, 25056 - 25068

DIABETES-INDUCED INNATE IMMUNE MEMORY DRIVES INFLAMMATION AND ATHEROSCLEROSIS, DESPITE RESTORATION OF NORMOGLYCAEMIA

Edgar L. et al, (2018), HEART, 104, A111 - A111

Fast, quantitative, murine cardiac 19F MRI/MRS of PFCE-labeled progenitor stem cells and macrophages at 9.4T.

Constantinides C. et al, (2018), PLoS One, 13

NITRIC OXIDE PROMOTES INSULIN-INDEPENDENT GLUCOSE UPTAKE AND PRESERVES CARDIAC FUNCTION AND ENERGETICS IN DIABETES

Ziberna K. et al, (2017), HEART, 103, A135 - A136

The Subcellular Localisation of Neuronal Nitric Oxide Synthase Determines the Downstream Effects of NO on Myocardial Function.

Carnicer R. et al, (2017), Cardiovasc Res

Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts.

Roselló-Lletí E. et al, (2016), Sci Rep, 6

Protein inhibitor of NOS1 plays a central role in the regulation of myocardial Ca2+ homeostasis in human heart failure

Rosello-Lleti E. et al, (2016), EUROPEAN HEART JOURNAL, 37, 912 - 912

Streptozotocin-induced diabetes mellitus increases the risk for atrial fibrillation

Ziberna K. et al, (2016), DIABETOLOGIA, 59, S12 - S12

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.

Reilly SN. et al, (2016), Sci Transl Med, 8

Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance.

Roselló-Lletí E. et al, (2016), Sci Rep, 6

Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.

Hashimoto T. et al, (2016), J Am Heart Assoc, 5

Loss of Myocardial nNOS Mediated by Upregulation of miR-31 in Human Atria Contributes to Begetting of Atrial Fibrillation

Liu X. et al, (2016), BIOPHYSICAL JOURNAL, 110, 451A - 451A

The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy

Duglan D. et al, (2015), EUROPEAN HEART JOURNAL, 36, 775 - 775

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