Contact information
+44 (0) 1865 572898
Colleges
Ileana Badi
PhD
Postdoctoral Researcher
My principal research interests lie in understanding the cellular and molecular mechanisms leading to cardiovascular disease. I obtained my Ph.D. in 2008 at the University of Insubria (Italy), where I studied the role of the transcription factor Ankrd1 in the pathogenesis of the rare congenital heart disease Total Anomalous Pulmonary Venous Return (TAPVR). Hence, I decided to deepen my knowledge on the transcriptional control of cardiac development in Professor Vincent M. Christoffels’s lab at the University of Amsterdam. There, I studied the transcriptional regulation of Tbx3 gene that encodes a transcription factor important for the conduction system and arterial pole morphogenesis. At this point I felt the need to move towards more translational studies; thus, I spent six years at the Centro Cardiologico Monzino, in Milan, where I focused my attention on the role of miR-34a in vascular “inflammaging” and vascular calcification, as this microRNA could be a promising therapeutic target for cardiovascular disease. In June 2018 I joined The Oxford Translational Cardiovascular Research Group, that superbly combines basic science and clinical research. Here, I am keen on studying how the cross-talk between adipose tissue and the cardiovascular system can affect cardiovascular disease.
Key publications
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Journal article
Badi I. and Antoniades C., (2021), Circulation, 143, 160 - 162
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Journal article
Akoumianakis I. et al, (2019), Sci Transl Med, 11
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Journal article
Akoumianakis I. et al, (2020), Sci Transl Med, 12
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Journal article
Badi I. et al, (2018), Arterioscler Thromb Vasc Biol, 38, 2079 - 2090
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Journal article
Badi I. et al, (2015), J Gerontol A Biol Sci Med Sci, 70, 1304 - 1311
Recent publications
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Role of Human Epicardial Adipose Tissue-Derived miR-92a-3p in Myocardial Redox State
Journal article
BADI I., (2023), Journal of the American College of Cardiology
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Journal article
Kotanidis CP. et al, (2022), Lancet Digit Health
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Journal article
Badi I. et al, (2022), Frontiers in Cell and Developmental Biology, 10
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Conference paper
Polkinghorne M. et al, (2022), HEART, 108, A143 - A144
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Journal article
Kondo H. et al, (2021), Eur Heart J, 42, 4947 - 4960