Publications — Radcliffe Department of Medicine

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Varicella-Zoster Virus ORF9 Is an Antagonist of the DNA Sensor cGAS

Hertzog J. et al, (2020)

Deoxyguanosine is a TLR7 agonist.

Davenne T. et al, (2019), Eur J Immunol

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection.

Rigby RE. et al, (2019), Sci Rep, 9

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.

Hansen AL. et al, (2018), Proc Natl Acad Sci U S A, 115, E7768 - E7775

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.

Hertzog J. et al, (2018), Eur J Immunol, 48, 1120 - 1136

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.

Mackenzie KJ. et al, (2016), EMBO J, 35, 831 - 844

RNA degradation in antiviral immunity and autoimmunity

Rigby RE. and Rehwinkel J., (2015), Trends in Immunology, 36, 179 - 188

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

Rigby RE. et al, (2014), EMBO J, 33, 542 - 558

SAMHD1-dependent retroviral control and escape in mice

Rehwinkel J. et al, (2013), RETROVIROLOGY, 10, S28 - S28

SAMHD1-dependent retroviral control and escape in mice

Rehwinkel J. et al, (2013), EMBO Journal, 32, 2454 - 2462

SAMHD1-dependent retroviral control and escape in mice.

Rehwinkel J. et al, (2013), Retrovirology, 10, P70 - P70

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

Reijns MAM. et al, (2012), Cell, 149, 1008 - 1022

Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid.

Pohjoismäki JLO. et al, (2010), J Mol Biol, 397, 1144 - 1155

Nucleic acid-mediated inflammatory diseases.

Rigby RE. et al, (2008), Bioessays, 30, 833 - 842

Accurate and reliable high-throughput detection of copy number variation in the human genome.

Fiegler H. et al, (2006), Genome Res, 16, 1566 - 1574

Finishing the euchromatic sequence of the human genome.

International Human Genome Sequencing Consortium None., (2004), Nature, 431, 931 - 945

Include forthcoming?