Publications — Radcliffe Department of Medicine

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Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.

Hazlehurst JM. et al, (2022), Metabol Open, 14

The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation.

Dearlove DJ. et al, (2022), Physiol Rep, 10

Obesity due to Steroid Receptor Coactivator-1 deficiency is associated with endocrine and metabolic abnormalities.

Cacciottolo TM. et al, (2022), J Clin Endocrinol Metab

Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice.

Pramfalk C. et al, (2022), J Intern Med

Metformin maintains intrahepatic triglyceride content through increased hepatic de novo lipogenesis.

Green CJ. et al, (2022), Eur J Endocrinol

Dysregulation of hepatic metabolism with obesity: factors influencing glucose and lipid metabolism

Nagarajan SR. et al, (2021), Proceedings of the Nutrition Society, 1 - 23

Bariatric surgery restores dysregulated hepatic lipid metabolism and promotes regression across the spectrum of NAFLD

Dempster N. et al, (2021), OBESITY SURGERY, 31, S16 - S16

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease.

Luukkonen PK. et al, (2021), J Hepatol

Overfeeding Saturated Fat Increases LDL (Low-Density Lipoprotein) Aggregation Susceptibility While Overfeeding Unsaturated Fat Decreases Proteoglycan-Binding of Lipoproteins.

Ruuth M. et al, (2021), Arterioscler Thromb Vasc Biol

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice.

Nasteska D. et al, (2021), JCI Insight, 6

Adipocyte NR1D1 dictates adipose tissue expansion during obesity.

Hunter AL. et al, (2021), Elife, 10

Dietary carbohydrates and fats in nonalcoholic fatty liver disease

Yki-Järvinen H. et al, (2021), Nature Reviews Gastroenterology & Hepatology

The influence of nutritional state on the fatty acid composition of circulating lipid fractions: implications for their use as biomarkers of dietary fat intake

HODSON L. et al, (2021), Upsala Journal of Medical Sciences

Physiological and pathophysiological concentrations of fatty acids induce lipid droplet accumulation and impair functional performance of tissue engineered skeletal muscle.

Turner MC. et al, (2021), J Cell Physiol

The role of 5-reduction in physiology and metabolic disease: evidence from cellular, pre-clinical and human studies.

Nikolaou N. et al, (2021), J Steroid Biochem Mol Biol, 207

β-Hydroxybutyrate Oxidation in Exercise Is Impaired by Low-Carbohydrate and High-Fat Availability.

Dearlove DJ. et al, (2021), Front Med (Lausanne), 8

Editorial: Foods and Macronutrients in NAFLD: Associations, Effects and Mechanisms.

Rosqvist F. et al, (2021), Front Nutr, 8

Lifestyle interventions affecting hepatic fatty acid metabolism.

Parry SA. et al, (2020), Curr Opin Clin Nutr Metab Care, 23, 373 - 379

Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism.

Hunter AL. et al, (2020), Proc Natl Acad Sci U S A

Adipocyte REVERBα dictates adipose tissue expansion during obesity

Louise Hunter A. et al, (2020)

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