A Mendelian randomisation study of the effect of body mass index on 52 causes of death among 125 000 Mexican adults with admixed ancestry
Gnatiuc Friedrichs L. et al, (2025), International Journal of Epidemiology
Alcohol and mortality in Mexico: prospective study of 150 000 adults.
Trichia E. et al, (2024), Lancet Public Health, 9, e907 - e915
Protein-truncating variants in BSN are associated with severe adult-onset 2 obesity, type 2 diabetes and fatty liver disease
EMBERSON J., (2024), Nature Genetics
Rare coding variants in CHRNB2 reduce the likelihood of smoking.
Rajagopal VM. et al, (2023), Nat Genet
Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells.
Torres JM. et al, (2023), Wellcome Open Res, 8
Mendelian randomization study of the relevance of blood pressure to vascular mortality among 150,000 participants in the mexico city prospective study
Turner M. et al, (2023), EUROPEAN HEART JOURNAL, 44
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.
Akbari P. et al, (2021), Science, 373
Abdominal and gluteo-femoral markers of adiposity and risk of vascular-metabolic mortality in a prospective study of 150,000 Mexican adults
GNATIUC L. et al, (2021), European Journal of Preventive Cardiology
Low-intensity daily smoking and cause-specific mortality in Mexico: prospective study of 150 000 adults
LACEY BEN. et al, (2021), International Journal of Epidemiology
Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals.
Wesolowska-Andersen A. et al, (2020), Elife, 9
A multi-tissue transcriptome analysis of human metabolites guides interpretability of associations based on multi-SNP models for gene expression
NDUNGU A. et al, (2020), American Journal of Human Genetics
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Flannick J. et al, (2019), Nature, 570, 71 - 76
Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data.
Fernández-Tajes J. et al, (2019), Genome Med, 11
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.
Mahajan A. et al, (2018), Nat Genet, 50, 1505 - 1513
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
Barbeira AN. et al, (2018), Nat Commun, 9
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci.
Thurner M. et al, (2018), Elife, 7
Mechanistic studies of the yeast polyamine oxidase Fms1: kinetic mechanism, substrate specificity, and pH dependence.
Adachi MS. et al, (2010), Biochemistry, 49, 10440 - 10448