Publications — Radcliffe Department of Medicine

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Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A.

Brierley CK. et al, (2023), bioRxiv

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.

Rodriguez-Meira A. et al, (2023), Nat Genet, 55, 1531 - 1541

A tale of two alleles: TP53 and transformation in MPNs.

Brierley C. and Psaila B., (2022), Blood, 139, 3567 - 3568

Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms

Li R. et al, (2022), BLOOD, 140, 1091 - 1092

Molecular Characterisation of Participants in the Phazar Trial Reveals Prognostic Impact of Mutations in Advanced-Phase-MPN

Brierley CK. et al, (2020), BLOOD, 136

Low participation rates and disparities in participation in interventional clinical trials for myelodysplastic syndromes.

Brierley CK. et al, (2020), Cancer, 126, 4735 - 4743

A NOVEL IN VITRO PLATFORM FOR THE PRIORITISATION AND VALIDATION OF INHIBITORS OF BONE MARROW FIBROSIS USING HUMAN BONE MARROW (BM) STROMAL CELLS

COLOMBO M. et al, (2020), HemaSphere, 4, 1 - 1168

Single-cell sequencing in hematology.

Brierley CK. and Mead AJ., (2020), Curr Opin Oncol, 32, 139 - 145

Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of EBMT and ISCT (JACIE).

Sharrack B. et al, (2020), Bone Marrow Transplant, 55, 283 - 306

Sugar thieves and addicts: nutrient subversion in JAK2 MPNs.

Brierley CK. and Psaila B., (2019), Blood, 134, 1778 - 1780

The effects of monoclonal anti-CD47 on RBCs, compatibility testing, and transfusion requirements in refractory acute myeloid leukemia.

Brierley CK. et al, (2019), Transfusion, 59, 2248 - 2254

Impact of graft-versus-lymphoma effect on outcomes after reduced intensity conditioned-alemtuzumab allogeneic haematopoietic stem cell transplantation for patients with mature lymphoid malignancies.

Brierley CK. et al, (2019), Br J Haematol, 184, 547 - 557

Response.

Brierley CK. and Pavord S., (2019), Clin Med (Lond), 19

The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic review.

Fisher SA. et al, (2019), PLoS One, 14

Autologous Haematopoietic Stem Cell Transplantation for Crohn's Disease: A Retrospective Survey of Long-term Outcomes From the European Society for Blood and Marrow Transplantation.

Brierley CK. et al, (2018), J Crohns Colitis, 12, 1097 - 1103

Autoimmune cytopenias and thrombotic thrombocytopenic purpura.

Brierley CK. and Pavord S., (2018), Clin Med (Lond), 18, 335 - 339

Desmopressin use for minimising perioperative blood transfusion.

Desborough MJ. et al, (2017), Cochrane Database Syst Rev, 7

Acute monoblastic leukemia presenting with striking periorbital and periauricular infiltration.

Brierley CK. and Eyre TA., (2017), Blood, 129

Hyperferritinemia in Pediatric Acute Lymphoblastic Leukemia: What Does it Mean?

Brierley CK. et al, (2017), J Pediatr Hematol Oncol, 39

Outcomes and Impact of Donor Lymphocyte Infusion after Reduced Intensity Conditioned-Alemtuzumab Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Mature Lymphoid Malignancies

Brierley CK. et al, (2016), BLOOD, 128

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