Senior Clinical Research Manager
Research into ways to prevent cardiovascular disease is a key component of activity within CCRF, this includes a major stream of work focussed on pregnancy complications such as preeclampsia and preterm birth. As a qualified midwife, Yvonne has responsibility for midwifery related research within the facility.
She works on a variety of projects including CAREFOL-HT (Clinical Antenatal Randomised study to Characterise key roles of Tetrahydrofolate in Hypertensive Pregnancies) investigating a nutritional supplement in pregnancy, the CHAPTER study (Cardiovascular Health Assessment of Preterm and Term born children) examining how pregnancy complications may affect the way hearts and blood vessels of children develop. POP-HT (Physician Optimised Postpartum Hypertension Treatment) looking at the impact blood pressure control has on women with preeclampsia or gestational hypertension. Her other research interests include Gestational Diabetes Mellitus (GDM). She is currently involved in a feasibility study called STAY ACTIVE, a multi-component lifestyle intervention, examining activity in pregnancy for women with a diagnosis of GDM.
Yvonne runs the Patient Participant Involvement (PPI) group for the department. This involves inviting previous participants and members of the public to be involved at the ideas stage of our future research.
Effect of Moderate to High Intensity Aerobic Exercise on Blood Pressure in Young Adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial
LEESON C., (2022), EClinicalMedicine
Short-Term Postpartum Blood Pressure Self-Management and Long-Term Blood Pressure Control: A Randomized Controlled Trial.
Kitt JA. et al, (2021), Hypertension, 78, 469 - 479
Clinical Implications of the NICE 2015 Criteria for Gestational Diabetes Mellitus.
Bhatia M. et al, (2018), J Clin Med, 7
Neonatal autonomic function after pregnancy complications and early cardiovascular development.
Aye CYL. et al, (2018), Pediatr Res, 84, 85 - 91
Comparing the Efficacy of a Mobile Phone-Based Blood Glucose Management System With Standard Clinic Care in Women With Gestational Diabetes: Randomized Controlled Trial.
Mackillop L. et al, (2018), JMIR Mhealth Uhealth, 6