BA (hons), BMBCh (hons), MRCP, DPhil (Oxon)
Associate Professor of Cardiovascular Medicine
- British Heart Foundation Intermediate Clinical Research Fellow
- Deputy Clinical Director of OCMR
- Honorary Consultant Cardiologist
After studying medicine at Pembroke College (1996-2002) I completed the Royal College Examinations and specialized in Cardiology. In 2005 I was awarded a Wellcome Trust Junior Research Fellowship to complete my DPhil in Cardiovascular medicine at Oxford, where I used advanced cardiac magnetic resonance imaging and spectroscopy to study the effects of obesity and weight loss on myocardial metabolism and function. For this work I was awarded the American Heart Association Young Investigator Award for Nutrition Physical Activity and Metabolism (2008) and took up the role of Clinical Lecturer in Cardiovascular Medicine in Oxford in 2010 where I furthered my research into obesity. In 2015 I was appointed as an Honorary Consultant Cardiologist and Deputy Clinical Director or the University of Oxford Centre for Clinical Magnetic Resonance Research. I currently hold a British Heart Foundation Intermediate Clinical Research Fellowship and run a research group that uses advanced cardiac magnetic resonance imaging and spectroscopy to investigate the relationship between cardiac substrate metabolism, cardiac energetics and cardiac function in multiple diseases with a focus on obesity, bariatric surgery, heart failure and cardiac hypertrophy.
Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T
CLARKE W. et al, (2019), NMR in Biomedicine
The interplay between metabolic alterations, diastolic strain rate and exercise capacity in mild heart failure with preserved ejection fraction: a cardiovascular magnetic resonance study.
Mahmod M. et al, (2018), J Cardiovasc Magn Reson, 20
Very low calorie diets are associated with transient ventricular impairment before reversal of diastolic dysfunction in obesity.
Rayner JJ. et al, (2018), Int J Obes (Lond)
Hyperpolarised magnetic resonance for in vivo real-time metabolic imaging.
Apps A. et al, (2018), Heart, 104, 1484 - 1491
Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance.
Lewis AJM. et al, (2018), Circ Res, 122, 1084 - 1093