Contact information
Research groups
Colleges
Nikolaos Sousos
MD | MSc (Distinction)
Clinical Research Fellow &
DPhil Student (CRUK-Oxford Centre)
I trained in medicine (MD, and MSc in Medical Research Methodology) and haematology (CCT in Haematology) in Aristotle University of Thessaloniki.
Currently, I am a Clinical Research Fellow, funded by Cancer Research UK, attending the DPhil in Medical Sciences programme, offered by Radcliffe Department of Medicine, University of Oxford. I am based in the MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, supervised by Professor Adam Mead. My research project focuses on the genetic lineage tracing in myeloproliferative neoplasms, with a special interest in the megakaryocyte/platelet-biased haematopoiesis.
My research is closely linked with my clinical practice, based at the Department of Clinical Haematology, The Churchill Hospital, Oxford University Hospitals NHS Foundation Trust.
Key publications
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Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
Journal article
Louka E. et al, (2021), J Exp Med, 218
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Artificial intelligence-based morphological fingerprinting of megakaryocytes: a new tool for assessing disease in MPN patients.
Journal article
Sirinukunwattana K. et al, (2020), Blood Adv, 4, 3284 - 3294
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Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis.
Journal article
Sousos N. et al, (2020), Hemasphere, 4
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Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.
Journal article
Psaila B. et al, (2020), Mol Cell, 78, 477 - 492.e8
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Low-dose methotrexate: potential clinical impact on haematological and constitutional symptoms in myeloproliferative neoplasms.
Journal article
Francis S. et al, (2019), Br J Haematol, 187, e69 - e72
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Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.
Journal article
Rodriguez-Meira A. et al, (2019), Mol Cell, 73, 1292 - 1305.e8