Nikolaos Sousos

MD | MSc (Distinction)

Clinical Research Fellow &

DPhil Student

I trained in medicine (MD, and MSc in Medical Research Methodology) and haematology (CCT in Haematology) in Aristotle University of Thessaloniki.

Currently, I am a Clinical Research Fellow, funded by Cancer Research UK, attending the DPhil in Medical Sciences programme, offered by Radcliffe Department of Medicine, University of Oxford. I am based in the MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, supervised by Professor Adam Mead. My research project focuses on the genetic lineage tracing in myeloproliferative neoplasms, with a special interest in the megakaryocyte/platelet-biased haematopoiesis.

My research is closely linked with my clinical practice, based at the Department of Clinical Haematology, The Churchill Hospital, Oxford University Hospitals NHS Foundation Trust.

Key publications

In utero origin of myelofibrosis presenting in adult monozygotic twins
Journal article

Sousos N. et al, (2022), Nature Medicine
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
Journal article

COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk None. and COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium None., (2022), Cell, 185, 916 - 938.e58
Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.
Journal article

Psaila B. et al, (2020), Mol Cell, 78, 477 - 492.e8
Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.
Journal article

Rodriguez-Meira A. et al, (2019), Mol Cell, 73, 1292 - 1305.e8
Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis.
Journal article

Sousos N. et al, (2020), Hemasphere, 4
Artificial intelligence-based morphological fingerprinting of megakaryocytes: a new tool for assessing disease in MPN patients.
Journal article

Sirinukunwattana K. et al, (2020), Blood Adv, 4, 3284 - 3294
Low-dose methotrexate: potential clinical impact on haematological and constitutional symptoms in myeloproliferative neoplasms.
Journal article

Francis S. et al, (2019), Br J Haematol, 187, e69 - e72

More publications