Websites
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British Heart Foundation
Funder
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NO Society
10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
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Nitric Oxide Society
Advancing basic and applied scientific research to fully realize the impact of Nitric Oxide on mankind.
Mark Crabtree
BSc (Hons), PhD
Visiting Scientist
- British Heart Foundation Intermediate Basic Science Research Fellow
Mark Crabtree is a British Heart Foundation Intermediate Basic Science Research Fellow and became a Group Leader and University Research Lecturer within the Division of Cardiovascular Medicine in 2015. His research group focuses on understanding the mechanisms of nitric oxide and redox signalling in molecular models of cardiovascular disease.
He began his postdoctoral research with Professor Keith Channon in 2006 and he held an internal University of Oxford British Heart Foundation Centre of Research Excellence Transition Fellowship (2012-2015). Mark did a collaborative PhD with the University of Surrey and Weill Medical College of Cornell University in New York City, having completed his BSc at the University of Surrey in 2001.
Mark is an active council member for the Nitric Oxide Society and is the meeting Chair for the International Nitric Oxide Society Conference being held in Oxford in in 2018.
His research interests focus on metabolomic and proteomic approaches to understand the impact of redox alterations in molecular and mouse models of cardiovascular homeostasis and disease.
Recent publications
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Isolation and In vitro Culture of Bone Marrow-Derived Macrophages for the Study of NO-Redox Biology.
Journal article
Diotallevi M. et al, (2022), J Vis Exp
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Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: a randomized trial of atorvastatin.
Journal article
Jayaram R. et al, (2022), Cardiovasc Res, 118, 184 - 195
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Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth.
Journal article
Chuaiphichai S. et al, (2021), Hypertension
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Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine.
Journal article
CRABTREE M. et al, (2021), Biochemical Society Transactions
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Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine.
Journal article
DIOTALLEVI M. et al, (2021), Biochemical Society Transactions