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Luke Payne

PhD; MRes; BSc (Hons)

Postdoctoral Researcher

I am a postdoctoral researcher in Prof Ellie Tzima’s laboratory in the Division of Cardiovascular Medicine. My current research focuses on how protein translation machinery interacts with and effects the cytoskeleton, using a number of molecular biology techniques including co-immunoprecipitation, high through-put plate reader assays and cloning.

Protein synthesis is a spatially and temporally coordinated process involving a vast array of components that precisely tune the organismal proteome. Protein translation machinery has been shown to interact with the cytoskeleton. However, there have been limited studies on how these two important cellular processes interact and regulate each other.

Before joining the RDM, I completed my PhD in Clinical Medicine Research at Imperial College London. My thesis was focused on identifying and characterising endothelial isoforms of the ETS transcription factor ERG.